Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL704811 | 1.00 | MEN1 (0.33) | MEN1ALDH1A1LMNAPOLBGAA | |
| SCHEMBL709596 | 0.82 | MEN1 (0.31) | MEN1ALDH1A1LMNAPOLBGAA | |
| SCHEMBL709595 | 0.82 | MEN1 (0.31) | MEN1ALDH1A1LMNAPOLBGAA | |
| SCHEMBL704130 | 0.76 | LMNA (0.34) | MEN1LMNAPOLBMAPTKMT2A | |
| SCHEMBL704131 | 0.76 | LMNA (0.34) | MEN1LMNAPOLBMAPTKMT2A | |
| SCHEMBL703955 | 0.75 | PIK3CA (0.32) | — | |
| SCHEMBL702580 | 0.75 | OGA (0.39) | MEN1ALDH1A1LMNAGAAMAPT | |
| SCHEMBL702579 | 0.75 | OGA (0.39) | MEN1ALDH1A1LMNAGAAMAPT | |
| SCHEMBL650831 | 0.74 | MAPT (0.43) | MEN1LMNAPOLBMAPTRECQL | |
| SCHEMBL650832 | 0.74 | MAPT (0.43) | MEN1LMNAPOLBMAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423204-A1 | THIAZOLIDINONE DERIVATIVE | SBI Biotech Co., Ltd. (JP) | 2012-02-29 | — | — | EP | disclosed |