Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 10/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.36 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.36 |
| ▸ | TESK1 | Q15569 | 1/20 | 0.36 |
| ▸ | TESK2 | Q96S53 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL702580 | 1.00 | OGA (0.39) | OGAMAPTMEN1KMT2ALMNA | |
| SCHEMBL702258 | 0.88 | SETD1B (0.33) | OGA | |
| SCHEMBL702257 | 0.88 | SETD1B (0.33) | OGA | |
| SCHEMBL701908 | 0.87 | KDM4E (0.37) | OGAMEN1KMT2AHTTKDM4E | |
| SCHEMBL701907 | 0.87 | KDM4E (0.37) | OGAMEN1KMT2AHTTKDM4E | |
| SCHEMBL704131 | 0.82 | LMNA (0.34) | OGAMAPTMEN1KMT2ALMNA | |
| SCHEMBL704130 | 0.82 | LMNA (0.34) | OGAMAPTMEN1KMT2ALMNA | |
| SCHEMBL702367 | 0.81 | OGA (0.35) | OGAMAPTMEN1KMT2ALMNA | |
| SCHEMBL702368 | 0.81 | OGA (0.35) | OGAMAPTMEN1KMT2ALMNA | |
| SCHEMBL717617 | 0.80 | OGA (0.38) | OGAMAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423204-A1 | THIAZOLIDINONE DERIVATIVE | SBI Biotech Co., Ltd. (JP) | 2012-02-29 | — | — | EP | disclosed |