Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 14/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL590532 | 0.83 | EPHX1 (0.59) | EPHX1ACHEALDH1A1ATMHPGD | |
| SCHEMBL10724669 | 0.79 | MGAM (0.42) | ALDH1A1MAPTRAB9A | |
| SCHEMBL9197261 | 0.79 | EPHX1 (0.55) | EPHX1ACHEALDH1A1ATMHPGD | |
| SCHEMBL27907267 | 0.79 | EPHX1 (0.47) | EPHX1ACHEALDH1A1ATM | |
| SCHEMBL590531 | 0.78 | EPHX1 (0.53) | EPHX1ACHEALDH1A1ATMHPGD | |
| SCHEMBL9395279 | 0.78 | EPHX1 (0.53) | EPHX1ACHEALDH1A1ATMHPGD | |
| SCHEMBL28436498 | 0.78 | EPHX1 (0.53) | EPHX1ACHEALDH1A1ATMHPGD | |
| SCHEMBL7447192 | 0.78 | EPHX1 (0.53) | EPHX1ACHEALDH1A1ATMHPGD | |
| SCHEMBL11627977 | 0.78 | ALDH1A1 (0.58) | EPHX1ACHEALDH1A1ATMHPGD | |
| SCHEMBL5138408 | 0.77 | EPHX1 (0.69) | EPHX1ACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003018019-A2 | NEW USE OF CYCLIC COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-03-06 | — | — | WO | disclosed |
| EP-1259499-A1 | THIAZEPINYL HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-27 | — | — | EP | disclosed |
| WO-2001060808-A1 | THIAZEPINYL HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-08-23 | — | — | WO | disclosed |