Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 14/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL590532 | 0.91 | EPHX1 (0.59) | EPHX1ALDH1A1ACHEATMHPGD | |
| SCHEMBL590531 | 0.84 | EPHX1 (0.53) | EPHX1ALDH1A1ACHEATMHPGD | |
| SCHEMBL28436498 | 0.84 | EPHX1 (0.53) | EPHX1ALDH1A1ACHEATMHPGD | |
| SCHEMBL7447192 | 0.84 | EPHX1 (0.53) | EPHX1ALDH1A1ACHEATMHPGD | |
| SCHEMBL9395279 | 0.84 | EPHX1 (0.53) | EPHX1ALDH1A1ACHEATMHPGD | |
| SCHEMBL11627977 | 0.84 | ALDH1A1 (0.58) | EPHX1ALDH1A1ACHEATMHPGD | |
| SCHEMBL5138408 | 0.84 | EPHX1 (0.69) | EPHX1ALDH1A1ACHE | |
| SCHEMBL6866097 | 0.83 | EPHX1 (0.52) | EPHX1ALDH1A1ACHEATMHPGD | |
| SCHEMBL4451188 | 0.83 | RAB9A (0.61) | EPHX1ALDH1A1ACHEATMHPGD | |
| SCHEMBL5936326 | 0.82 | EPHX1 (0.73) | EPHX1ACHETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687249-A1 | BALANOIDS | ELI LILLY AND COMPANY (US) | 1995-12-20 | — | — | EP | disclosed |
| WO-1994020062-A2 | BALANOIDS AS PROTEIN KINASE C INHIBITORS | ELI LILLY AND COMPANY (US) | 1994-09-15 | — | — | WO | disclosed |