Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNE1 | P15382 | 1/20 | 0.55 |
| ▸ | CCR1 | P32246 | 1/20 | 0.55 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.47 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.44 |
| ▸ | SCD | O00767 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27635508 | 0.84 | KCNE1 (0.55) | KCNE1CCR1KCNQ1SMN1; SMN2MEN1 | |
| SCHEMBL6094780 | 0.83 | LIPG (0.42) | KCNE1CCR1KCNQ1SMN1; SMN2MEN1 | |
| SCHEMBL5314622 | 0.83 | KCNE1 (0.67) | KCNE1CCR1KCNQ1SMN1; SMN2MEN1 | |
| SCHEMBL13041229 | 0.82 | KCNE1 (0.69) | KCNE1CCR1KCNQ1SMN1; SMN2MEN1 | |
| SCHEMBL6094550 | 0.82 | KCNH2 (0.54) | KCNE1CCR1KCNQ1SMN1; SMN2MEN1 | |
| SCHEMBL6094737 | 0.82 | CYP2C9 (0.56) | KCNE1CCR1KCNQ1SMN1; SMN2MEN1 | |
| SCHEMBL6017760 | 0.82 | SMN1; SMN2 (0.57) | KCNE1CCR1KCNQ1SMN1; SMN2MEN1 | |
| SCHEMBL1150575 | 0.82 | KCNE1 (0.56) | KCNE1CCR1KCNQ1SMN1; SMN2MEN1 | |
| SCHEMBL1150195 | 0.82 | KCNE1 (0.56) | KCNE1CCR1KCNQ1SMN1; SMN2MEN1 | |
| SCHEMBL12776746 | 0.81 | CYP2C9 (0.55) | KCNE1CCR1KCNQ1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004062613-A2 | HIV INTEGRASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-07-29 | — | — | WO | disclosed |