Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 4/20 | 0.44 |
| ▸ | FABP3 | P05413 | 2/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | RPA1 | P27694 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.40 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.40 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL237314 | 0.86 | FABP4 (0.46) | FABP4FABP3FABP5MYCRPA1 | |
| SCHEMBL7553864 | 0.83 | FABP4 (0.44) | FABP4FABP3FABP5MYCRPA1 | |
| SCHEMBL28422371 | 0.81 | PPARG (0.44) | FABP4MYCRPA1MCL1PPARG | |
| SCHEMBL28891243 | 0.81 | FABP4 (0.42) | FABP4FABP3FABP5MYCRPA1 | |
| SCHEMBL28432617 | 0.81 | MEN1 (0.44) | FABP4FABP3FABP5MYCRPA1 | |
| SCHEMBL28771673 | 0.81 | ELANE (0.45) | FABP4FABP3FABP5MYCRPA1 | |
| SCHEMBL965339 | 0.80 | TDP1 (0.47) | PPARGSMN1; SMN2L3MBTL1MEN1KMT2A | |
| SCHEMBL31438969 | 0.80 | THRB (0.45) | FABP4FABP3FABP5MYCRPA1 | |
| SCHEMBL28425508 | 0.78 | KDM4E (0.48) | FABP4RPA1MCL1PPARGPPARA | |
| SCHEMBL8463126 | 0.77 | POLB (0.56) | PPARGPPARAL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301464-A1 | BIPHENYLCARBOXYLIC ACID AMIDES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | Boehringer Ingelheim Pharma KG (DE) | 2003-04-16 | — | — | EP | disclosed |
| WO-2002004403-A1 | BIPHENYLCARBOXYLIC ACID AMIDES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-01-17 | — | — | WO | disclosed |