Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALPG | P10696 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2288655 | 0.80 | MAPT (0.47) | MAPTHPGDSMN1; SMN2MGLLHSD17B10 | |
| SCHEMBL1454790 | 0.78 | HPGD (0.45) | MAPTHPGDSMN1; SMN2MGLLHSD17B10 | |
| SCHEMBL24097655 | 0.77 | HPGD (0.39) | MAPTHPGDSMN1; SMN2MGLLHSD17B10 | |
| SCHEMBL342299 | 0.74 | CA12 (0.54) | MAPTHPGDSMN1; SMN2MGLLHSD17B10 | |
| SCHEMBL2374205 | 0.74 | MAPT (0.41) | MAPTHPGDSMN1; SMN2MGLLHSD17B10 | |
| SCHEMBL7051052 | 0.74 | ALDH1A1 (0.45) | MAPTHPGDSMN1; SMN2MGLLHSD17B10 | |
| SCHEMBL776859 | 0.74 | MAPT (0.41) | MAPTHPGDSMN1; SMN2MGLLHSD17B10 | |
| SCHEMBL777004 | 0.74 | MAPT (0.41) | MAPTHPGDSMN1; SMN2MGLLHSD17B10 | |
| SCHEMBL10774029 | 0.74 | HPGD (0.41) | MAPTHPGDSMN1; SMN2MGLLHSD17B10 | |
| SCHEMBL10708211 | 0.73 | ALDH1A1 (0.41) | MAPTHPGDHSD17B10ALDH1A1MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1304325-A1 | 5-(M-CYANOBENZYLAMINO)PYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-04-23 | — | — | EP | disclosed |