Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MGLL | Q99685 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | PHGDH | O43175 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11205281 | 0.78 | MAPT (0.45) | MAPTHPGDMGLLSMN1; SMN2HSD17B10 | |
| SCHEMBL3073259 | 0.78 | MAPT (0.45) | MAPTHPGDMGLLSMN1; SMN2HSD17B10 | |
| SCHEMBL1454790 | 0.78 | HPGD (0.45) | MAPTHPGDMGLLSMN1; SMN2HSD17B10 | |
| SCHEMBL3073488 | 0.78 | MAPT (0.56) | MAPTHPGDMGLLSMN1; SMN2HSD17B10 | |
| Hydrochloric Acid SCHEMBL11839902 | 0.76 | MAPT (0.43) | MAPTHPGDMGLLSMN1; SMN2HSD17B10 | |
| SCHEMBL16312724 | 0.75 | MAPT (0.43) | MAPTHPGDMGLLSMN1; SMN2HSD17B10 | |
| SCHEMBL8712481 | 0.75 | TSHR (0.50) | HPGDSMN1; SMN2ALDH1A1HTTCA2 | |
| SCHEMBL8715668 | 0.74 | HSD17B10 (0.61) | MAPTHPGDHSD17B10ALDH1A1NPC1 | |
| SCHEMBL10774029 | 0.74 | HPGD (0.41) | MAPTHPGDMGLLSMN1; SMN2HSD17B10 | |
| SCHEMBL342299 | 0.74 | CA12 (0.54) | MAPTHPGDMGLLSMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9023914-B2 | Nitrile rubbers and production thereof in organic solvents | LANXESS DEUTSCHLAND GMBH (DE) | 2015-05-05 | — | — | US | claimed |
| US-20140235744-A1 | PROCESS FOR PRODUCING NITRILE RUBBERS IN ORGANIC SOLVENTS | LANXESS DEUTSCHLAND GMBH (DE) | 2014-08-21 | — | — | US | claimed |
| US-20120283351-A1 | NITRILE RUBBERS AND PRODUCTION THEREOF IN ORGANIC SOLVENTS | LANXESS DEUTSCHLAND GMBH (DE) | 2012-11-08 | — | — | US | claimed |
| EP-3359580-B1 | POLYMER HAVING ANTIMICROBIAL AND/OR ANTIFOULING PROPERTIES | UNIV FREIBURG ALBERT LUDWIGS (DE) | 2022-03-30 | — | — | EP | disclosed |
| US-11078157-B1 | Compound embodiments that release H2S by reaction with a reactive compound and methods of making and using the same | UNIVERSITY OF OREGON (US) | 2021-08-03 | — | — | US | disclosed |
| US-10889726-B2 | Polymer having antimicrobial and/or antifouling properties | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2021-01-12 | — | — | US | disclosed |
| US-10858455-B2 | Process for the production of water and solvent-free nitrile rubbers | ARLANXEO DEUTSCHLAND GMBH (DE) | 2020-12-08 | — | — | US | disclosed |
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |
| US-20180327607-A1 | POLYMER HAVING ANTIMICROBIAL AND/OR ANTIFOULING PROPERTIES | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2018-11-15 | — | — | US | disclosed |
| US-20160369014-A1 | PROCESS FOR THE PRODUCTION OF WATER AND SOLVENT-FREE NITRILE RUBBERS | ARLANXEO DEUTSCHLAND GMBH (DE) | 2016-12-22 | — | — | US | disclosed |
| US-20160355514-A1 | PYRIDINYL AND PYRIMIDINYL SULFOXIDE AND SULFONE DERIVATIVES | VALO EARLY DISCOVERY, INC. | 2016-12-08 | — | — | US | disclosed |
| US-20040104377-A1 | Non-toxic corrosion-protection pigments based on rare earth elements | UNIVERSITY OF DAYTON | 2004-06-03 | — | — | US | disclosed |
| US-20040020568-A1 | Non-toxic corrosion-protection conversion coats based on rare earth elements | DAYTON, UNIVERSITY OF | 2004-02-05 | — | — | US | disclosed |
| US-20040016910-A1 | Non-toxic corrosion-protection rinses and seals based on rare earth elements | DAYTON, UNIVERSITY OF | 2004-01-29 | — | — | US | disclosed |
| US-20040011252-A1 | Non-toxic corrosion-protection pigments based on manganese | UNIVERSITY OF DAYTON | 2004-01-22 | — | — | US | disclosed |
| US-20030234063-A1 | Non-toxic corrosion-protection conversion coats based on cobalt | DAYTON, UNIVERSITY OF | 2003-12-25 | — | — | US | disclosed |
| US-20030230363-A1 | Non-toxic corrosion-protection rinses and seals based on cobalt | UNIVERSITY OF DAYTON | 2003-12-18 | — | — | US | disclosed |
| WO-2003060192-A1 | NON-TOXIC CORROSION-PROTECTION RINSES AND SEALS BASED ON COBALT | UNIVERSITY OF DAYTON (US) | 2003-07-24 | — | — | WO | disclosed |
| WO-2003060191-A2 | NON-TOXIC CORROSION-PROTECTION CONVERSION COATINGES ABSED ON COBALT | UNIVERSITY OF DAYTON (US) | 2003-07-24 | — | — | WO | disclosed |
| WO-2003060019-A1 | NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT | UNIVERSITY OF DAYTON (US) | 2003-07-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160355514-A1 | PYRIDINYL AND PYRIMIDINYL SULFOXIDE AND SULFONE DERIVATIVES | TPMT, TYMS, TYMP | MAPT 2256/4885HPGD 381/4885MGLL 2680/4885 |
| US-11078157-B1 | Compound embodiments that release H2S by reaction with a reactive compound and methods of making and using the same | CBS, SQOR, QSOX1 | MAPT 4757/4885HPGD 386/4885MGLL 2745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.