Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7260172 | 0.87 | PTGDR2 (0.53) | PTGDR2HDAC7LMNAL3MBTL1MAPK1 | |
| SCHEMBL28022867 | 0.85 | BACE1 (0.56) | PTGDR2HDAC7LMNAL3MBTL1MAPK1 | |
| SCHEMBL7053967 | 0.81 | FABP7 (0.42) | LMNAL3MBTL1TDP1BACE1ALDH1A1 | |
| SCHEMBL6220741 | 0.79 | FABP3 (0.53) | LMNAL3MBTL1MAPK1TDP1ALDH1A1 | |
| SCHEMBL29922550 | 0.79 | FABP3 (0.53) | LMNAL3MBTL1MAPK1TDP1ALDH1A1 | |
| SCHEMBL7052744 | 0.77 | BACE1 (0.58) | PTGDR2BACE1ALDH1A1KDM4ECNR2 | |
| SCHEMBL11962286 | 0.75 | ACHE (0.54) | PTGDR2L3MBTL1TDP1ALDH1A1HTT | |
| SCHEMBL7079259 | 0.75 | HDAC7 (0.57) | PTGDR2HDAC7L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL9228881 | 0.74 | NCOA1 (0.49) | PTGDR2HDAC7L3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL11609948 | 0.74 | KDM4E (0.48) | L3MBTL1MAPK1ALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301464-A1 | BIPHENYLCARBOXYLIC ACID AMIDES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | Boehringer Ingelheim Pharma KG (DE) | 2003-04-16 | — | — | EP | disclosed |
| WO-2002004403-A1 | BIPHENYLCARBOXYLIC ACID AMIDES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-01-17 | — | — | WO | disclosed |