SCHEMBL7049564

SCHEMBL7049564

O=C(CCCCCCCCC(=O)Oc1ccccc1Cl)Oc1ccccc1Cl

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.49
KMT2A Q03164 5/20 0.49
KDM4E B2RXH2 1/20 0.49
RECQL P46063 1/20 0.49
POLM Q9NP87 1/20 0.44
POLK Q9UBT6 1/20 0.44
POLL Q9UGP5 1/20 0.44
POLH Q9Y253 1/20 0.44
PTK2B Q14289 1/20 0.44
PKM P14618 1/20 0.44
CXCL8 P10145 1/20 0.44
BCHE P06276 1/20 0.43
PRSS1 P07477 1/20 0.43
PRSS2 P07478 1/20 0.43
PRSS3 P35030 1/20 0.43
HPGD P15428 2/20 0.41
RXRA P19793 1/20 0.41
RXRB P28702 1/20 0.41
TP53 P04637 1/20 0.41
HTT P42858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8496997 1.00 MEN1 (0.49) MEN1KMT2AKDM4ERECQLPOLM
SCHEMBL8498810 0.98 KMT2A (0.50) MEN1KMT2AKDM4ERECQLPOLM
SCHEMBL13505905 0.94 MEN1 (0.50) MEN1KMT2AKDM4ERECQLPTK2B
SCHEMBL27508353 0.92 KMT2A (0.57) MEN1KMT2AKDM4ERECQLPOLM
SCHEMBL8088316 0.92 KMT2A (0.57) MEN1KMT2AKDM4ERECQLPOLM
SCHEMBL9322247 0.92 KMT2A (0.57) MEN1KMT2AKDM4ERECQLPOLM
SCHEMBL8496813 0.90 PTK2B (0.47) MEN1KMT2AKDM4ERECQLPTK2B
SCHEMBL8676312 0.90 KDM4E (0.59) MEN1KMT2AKDM4ERECQLPOLM
SCHEMBL5706039 0.88 MEN1 (0.65) MEN1KMT2AKDM4ERECQLPOLM
SCHEMBL27775316 0.86 L3MBTL1 (0.51) MEN1KMT2AKDM4ERECQLPTK2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1115792-B1 WEATHERABLE BLENDS OF POLYCARBONATES WITH ARYLATE POLYMERS GEN ELECTRIC (US) 2003-04-23 EP disclosed
EP-1115792-A1 WEATHERABLE BLENDS OF POLYCARBONATES WITH ARYLATE POLYMERS GENERAL ELECTRIC COMPANY (US) 2001-07-18 EP disclosed
US-6143839-A THERMOPLASTIC ARYLATE POLYMER COMPRISING UNITS DERIVED FROM A RESORCINOL OR ALKYLRESORCINOL ISOPHTHALATE-TEREPHTHALATE IMPROVES COLOR STABILITY OR GLOSS RETENTION OF THE POLYCARBONATE; ARTICLES MADE FROM THE BLEND GENERAL ELECTRIC COMPANY (US) 2000-11-07 US disclosed
WO-2000015718-A1 WEATHERABLE BLENDS OF POLYCARBONATES WITH ARYLATE POLYMERS GENERAL ELECTRIC COMPANY (US) 2000-03-23 WO disclosed