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Benzenesulfonamide

Benzenesulfonamide

SCHEMBL7049598

Cc1ccnc(-c2nc(C(F)(F)F)cn2NS(=O)(=O)c2ccccc2)c1.NS(=O)(=O)c1ccccc1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ PTGS2 P35354 20/20 0.61
▸ PTGS1 P23219 9/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzenesulfonamide SCHEMBL7189185 0.82 PTGS2 (0.61) PTGS2PTGS1
Benzenesulfonamide SCHEMBL7048970 0.82 PTGS2 (0.62) PTGS2PTGS1
SCHEMBL7773790 0.81 PTGS2 (0.42) PTGS2PTGS1
Benzenesulfonamide SCHEMBL7932083 0.81 PTGS2 (0.62) PTGS2PTGS1
Benzenesulfonamide SCHEMBL7050658 0.81 PTGS2 (0.62) PTGS2PTGS1
SCHEMBL215247 0.76 PTGS2 (1.00) PTGS2PTGS1
SCHEMBL8346344 0.76 PTGS2 (0.55) PTGS2PTGS1
Sulfamide SCHEMBL4638289 0.76 PTGS2 (0.79) PTGS2PTGS1
SCHEMBL7567963 0.76 PTGS2 (0.78) PTGS2PTGS1
SCHEMBL7868339 0.75 PTGS2 (0.45) PTGS2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1299122-A2 COMBINATION OF A COX-2 INHIBITOR AND A VASOMODULATOR FOR TREATING PAIN AND HEADACHE PAIN Pharmacia Corporation (US) 2003-04-09 — — EP claimed
WO-2002005799-A2 COMBINATION OF A COX-2 INHIBITOR AND A VASOMODULATOR FOR TREATING PAIN AND HEADACHE PAIN PHARMACIA CORPORATION (US) 2002-01-24 — — WO claimed