Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | NPY1R | P25929 | 1/20 | 0.56 |
| ▸ | NPY2R | P49146 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3426467 | 0.86 | MAPT (0.69) | MAPTLMNAMAPK1ALDH1A1NPY1R | |
| SCHEMBL16109571 | 0.83 | TSHR (0.58) | MAPTLMNAALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL28453421 | 0.82 | LMNA (0.77) | MAPTLMNAMAPK1ALDH1A1NPY1R | |
| SCHEMBL28451012 | 0.79 | MEN1 (0.78) | MAPTLMNAMAPK1ALDH1A1NPY1R | |
| SCHEMBL8242227 | 0.79 | NPC1 (0.70) | MAPTLMNAMAPK1ALDH1A1NPY1R | |
| SCHEMBL3426163 | 0.79 | MAPT (0.66) | MAPTLMNAMAPK1ALDH1A1GAA | |
| SCHEMBL3425236 | 0.77 | MAPT (0.60) | MAPTLMNAMAPK1ALDH1A1GAA | |
| SCHEMBL4958469 | 0.76 | LMNA (0.74) | MAPTLMNAMAPK1ALDH1A1NPY1R | |
| SCHEMBL4957083 | 0.75 | LMNA (0.77) | MAPTLMNAMAPK1ALDH1A1NPY1R | |
| SCHEMBL4957089 | 0.75 | LMNA (1.00) | MAPTLMNAMAPK1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087053-A9 | DIPEPTIDYL PEPTIDASE INHIBITORS | SYRRX INC (US) | 2004-11-11 | — | — | WO | disclosed |