Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.42 |
| ▸ | NPC1 | O15118 | 7/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | TP53 | P04637 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6457047 | 0.87 | S1PR1 (0.58) | MAPTS1PR1MEN1KMT2ANISCH | |
| SCHEMBL6453045 | 0.83 | SMN1; SMN2 (0.40) | MAPTS1PR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7053110 | 0.83 | MAPT (0.42) | MAPTS1PR1MEN1KMT2ANISCH | |
| SCHEMBL6450392 | 0.82 | NPC1 (0.63) | MAPTS1PR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6456662 | 0.80 | RAB9A (0.43) | MAPTS1PR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6450253 | 0.78 | SMN1; SMN2 (0.63) | MAPTS1PR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6451277 | 0.75 | SMN1; SMN2 (0.50) | MAPTS1PR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6453548 | 0.75 | NR1H4 (0.41) | MAPTS1PR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6452503 | 0.74 | SMN1; SMN2 (0.48) | MAPTS1PR1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6448850 | 0.73 | SMN1; SMN2 (0.51) | MAPTS1PR1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004110351-A2 | HETEROCYCLIC COMPOUNDS FOR TREATING HEPATITIS C VIRUS | ANADYS PHARMACEUTICALS, INC. (US) | 2004-12-23 | — | — | WO | disclosed |