Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6451316 | 0.84 | MAPT (0.43) | MAPTL3MBTL1MEN1KMT2APOLB | |
| SCHEMBL7049815 | 0.83 | MAPT (0.48) | MAPTL3MBTL1MEN1KMT2AS1PR1 | |
| SCHEMBL6457047 | 0.81 | S1PR1 (0.58) | MAPTL3MBTL1MEN1KMT2AS1PR1 | |
| SCHEMBL6450875 | 0.79 | MAPT (0.56) | MAPTL3MBTL1KMT2APOLBNPC1 | |
| SCHEMBL6450392 | 0.77 | NPC1 (0.63) | MAPTL3MBTL1MEN1KMT2AS1PR1 | |
| SCHEMBL6448628 | 0.76 | MAPK1 (0.47) | MAPTL3MBTL1MEN1KMT2AS1PR1 | |
| SCHEMBL6449381 | 0.74 | NPC1 (0.58) | MAPTMEN1KMT2APOLBNPC1 | |
| SCHEMBL6452435 | 0.72 | MAPT (0.45) | MAPTL3MBTL1MEN1KMT2AS1PR1 | |
| SCHEMBL6454080 | 0.71 | MAPT (0.52) | MAPTL3MBTL1MEN1KMT2AS1PR1 | |
| SCHEMBL6454629 | 0.71 | CASP3 (0.54) | MAPTMEN1KMT2APOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004110351-A2 | HETEROCYCLIC COMPOUNDS FOR TREATING HEPATITIS C VIRUS | ANADYS PHARMACEUTICALS, INC. (US) | 2004-12-23 | — | — | WO | disclosed |