SCHEMBL704990

SCHEMBL704990

[SiH3]OCCCC(c1ccccc1)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 6/20 0.54
HTR2A P28223 6/20 0.54
SIGMAR1 Q99720 3/20 0.46
CYP19A1 P11511 4/20 0.43
KCNH2 Q12809 1/20 0.43
CYP2D6 P10635 1/20 0.40
TAAR1 Q96RJ0 1/20 0.39
GRM2 Q14416 1/20 0.39
GRM3 Q14832 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL705235 0.94 HRH1 (0.52) HRH1HTR2ASIGMAR1CYP19A1KCNH2
SCHEMBL702332 0.92 HRH1 (0.50) HRH1HTR2ASIGMAR1CYP19A1KCNH2
SCHEMBL702748 0.92 HRH1 (0.50) HRH1HTR2ASIGMAR1CYP19A1KCNH2
SCHEMBL242578 0.86 HRH1 (0.50) HRH1HTR2ASIGMAR1CYP19A1KCNH2
SCHEMBL7784138 0.82 HRH1 (0.58) HRH1HTR2ASIGMAR1CYP19A1KCNH2
SCHEMBL402332 0.78 HRH1 (0.59) HRH1HTR2ASIGMAR1CYP19A1KCNH2
SCHEMBL3959644 0.78 HRH1 (0.54) HRH1HTR2ASIGMAR1CYP19A1KCNH2
SCHEMBL7799318 0.78 HRH1 (0.54) HRH1HTR2ASIGMAR1CYP19A1KCNH2
SCHEMBL9073997 0.78 HRH1 (0.71) HRH1HTR2ASIGMAR1CYP19A1KCNH2
SCHEMBL466504 0.78 HRH1 (0.48) HRH1HTR2ASIGMAR1CYP19A1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016196256-A2 NON-AROMATIC DIFLUORO ANALOGUES OF RESORCYLIC ACID LACTONES UNIVERSITY OF NORTH CAROLINA AT GREENSBORO (US) 2016-12-08 WO claimed
EP-2635547-A1 CHIRAL INTERMEDIATES USEFUL FOR THE PREPARATION OF HYDROXYPHOSPHINE LIGANDS United Phosphorus Limited (IN) 2013-09-11 EP claimed
WO-2012059807-A1 CHIRAL INTERMEDIATES USEFUL FOR THE PREPARATION OF HYDROXYPHOSPHINE LIGANDS UNITED PHOSPHORUS LIMITED (IN) 2012-05-10 WO claimed
EP-4237008-A2 CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF Elucida Oncology, Inc. (US) 2023-09-06 EP disclosed
EP-4056604-B1 METHOD FOR PRODUCING COPOLYMER OF 1,3,7-OCTATRIENE AND STYRENE KURARAY CO (JP) 2023-08-02 EP disclosed
EP-3564280-B1 COPOLYMER OF 1, 3, 7-OCTATRIENE AND STYRENE AND HYDRIDE THEREOF KURARAY CO (JP) 2023-07-26 EP disclosed
EP-4163311-A1 COPOLYMER OF 1,3,7-OCTATRIENE AND ISOPRENE, HYDRIDE THEREOF, AND METHOD FOR PRODUCING SAID COPOLYMER Kuraray Co., Ltd. (JP) 2023-04-12 EP disclosed
EP-4163312-A1 COPOLYMER OF 1,3,7-OCTATRIENE AND ISOPRENE, HYDRIDE THEREOF, AND METHOD FOR PRODUCING SAID COPOLYMER Kuraray Co., Ltd. (JP) 2023-04-12 EP disclosed
EP-3564274-B1 1, 3, 7-OCTATRIENE POLYMER, HYDRIDE THEREOF, AND METHOD FOR PRODUCING SAID POLYMER KURARAY CO (JP) 2022-12-28 EP disclosed
EP-4103236-A1 FOLATE RECEPTOR TARGETED NANOPARTICLE DRUG CONJUGATES AND USES THEREOF Elucida Oncology, Inc. (US) 2022-12-21 EP disclosed
EP-4056604-A1 METHOD FOR PRODUCING COPOLYMER OF 1,3,7-OCTATRIENE AND STYRENE Kuraray Co., Ltd. (JP) 2022-09-14 EP disclosed
EP-1709155-A2 COMPOUNDS AND COMPOSITIONS FOR TREATING DYSPROLIFERATIVE DISEASES, AND METHODS OF USE THEREOF Kashfi, Khosrow (US) 2006-10-11 EP disclosed
EP-1690839-A1 FLEXIBLE SUBSTRATE AND COATING LIQUID Sumitomo Corporation (JP) 2006-08-16 EP disclosed
WO-2005065361-A2 COMPOUNDS AND COMPOSITIONS FOR TREATING DYSPROLIFERATIVE DISEASES, AND METHODS OF USE THEREOF KASHFI KHOSROW (US) 2005-07-21 WO disclosed
EP-1063252-B1 FLAME-RETARDANT RESIN, COMPOSITION THEREOF, AND PROCESS FOR PRODUCING THE SAME OTSUKA KAGAKU KK (JP) 2005-06-08 EP disclosed
US-6632891-B1 Obtained by an ester exchange reaction between the flame retardant phosphazene and the polycarbonate or polyester resin OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 2003-10-14 US disclosed
EP-1063252-A1 FLAME-RETARDANT RESIN, COMPOSITION THEREOF, AND PROCESS FOR PRODUCING THE SAME OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 2000-12-27 EP disclosed
EP-0593464-A1 BENZOIC ACID DERIVATIVES and their use as LTB4 inhibitors SMITHKLINE BEECHAM CORPORATION (US) 1994-04-27 EP disclosed
EP-0593464-A4 BENZOIC ACID DERIVATIVES. SMITHKLINE BEECHAM CORP (US) 1993-02-12 EP disclosed
WO-1991018601-A1 BENZOIC ACID DERIVATIVES SMITHKLINE BEECHAM CORPORATION (US) 1991-12-12 WO disclosed