SCHEMBL705011

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL23467048	0.88	NLRP3 (0.40)	NLRP3HTR2AHTR2CPOLBMPO
	SCHEMBL906048	0.81	PDGFRA (0.35)	NLRP3PDGFRACDK5TYRO3KHK
	SCHEMBL26997341	0.79	TMEM97 (0.34)	NLRP3KHKHTR2AHTR2CSLC22A12
	SCHEMBL16596067	0.79	GRM4 (0.43)	NLRP3PDGFRACDK5TYRO3KHK
	SCHEMBL4507507	0.79	GRM4 (0.43)	PDGFRACDK5TYRO3KHKSLC22A12
	SCHEMBL13322761	0.78	PDGFRA (0.55)	NLRP3PDGFRACDK5TYRO3HTR2A
	SCHEMBL683164	0.78	ADORA2A (0.43)	PDGFRACDK5TYRO3KHKHTR2A
	SCHEMBL25036653	0.78	NLRP3 (0.44)	NLRP3PDGFRACDK5TYRO3RET
	SCHEMBL5353366	0.77	KHK (0.39)	NLRP3KHK
	SCHEMBL18993246	0.77	MPO (0.45)	POLBMPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.