SCHEMBL7050455

SCHEMBL7050455

OC(F)C(F)C1CC2C=CC1C2

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
ALDH1A1 P00352 1/20 0.32
GAA P10253 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3874892 0.83 KDM4E (0.35) KDM4ELMNAALDH1A1GAATDP1
SCHEMBL5856382 0.78 KDM4E (0.33) KDM4ELMNAALDH1A1GAATDP1
SCHEMBL4608572 0.78 KDM4E (0.38) KDM4ELMNAALDH1A1GAATDP1
SCHEMBL1088788 0.74 NPC1 (0.36) KDM4ELMNAALDH1A1GAATDP1
SCHEMBL3364098 0.73 KDM4E (0.32) KDM4ELMNAALDH1A1GAATDP1
SCHEMBL4666821 0.71 KDM4E (0.33) KDM4ELMNAALDH1A1GAATDP1
SCHEMBL12729995 0.71 KDM4E (0.33) KDM4ELMNAALDH1A1GAATDP1
SCHEMBL11709367 0.70 KDM4E (0.32) KDM4ELMNAALDH1A1GAATDP1
SCHEMBL8770222 0.70 KDM4E (0.32) KDM4ELMNAALDH1A1GAATDP1
SCHEMBL11709370 0.70 KDM4E (0.32) KDM4ELMNAALDH1A1GAATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030219680-A1 Photoresists useful for microfabrication utilizing deep ultraviolet rays such as an excimer laser, x-rays such as synchrotron radiation, and electron beams JSR CORPORATION (JP) 2003-11-27 US disclosed