Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.34 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2478563 | 0.81 | ZDHHC20 (0.39) | DPP4ZDHHC20ZDHHC2TSHR | |
| SCHEMBL16776783 | 0.75 | TSHR (0.37) | TSHRBCL2A1 | |
| SCHEMBL308456 | 0.75 | — | — | |
| SCHEMBL1864607 | 0.75 | ZDHHC20 (0.38) | DPP4ZDHHC20ZDHHC2TSHR | |
| SCHEMBL5763404 | 0.73 | — | — | |
| SCHEMBL646634 | 0.73 | — | — | |
| SCHEMBL2654969 | 0.72 | DPP4 (0.52) | DPP4 | |
| SCHEMBL27473218 | 0.71 | TSHR (0.34) | TSHRBCL2A1 | |
| SCHEMBL8415448 | 0.71 | — | — | |
| SCHEMBL2813812 | 0.71 | DPP4 (0.46) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6605270-B1 | Removing iron from patient by orally administering therapeutically effective amount of polymer characterized by specified repeat unit, or heteropolymer thereof | GENZYME CORPORATION | 2003-08-12 | — | — | US | disclosed |
| EP-0699072-B1 | USE OF IRON-BINDING POLYMERS FOR THE MANUFACTURE OF A MEDICAMENT FOR ORAL ADMINISTRATION | GELTEX PHARMA INC (US) | 2003-04-23 | — | — | EP | disclosed |
| US-5702696-A | FOR TREATMENT OF IRON OVERLOAD DISORDERS | GELTEX PHARMACEUTICALS (US) | 1997-12-30 | — | — | US | disclosed |
| US-5487888-A | Iron-binding polymers for oral administration | GELTEX, INC. (US) | 1996-01-30 | — | — | US | disclosed |
| WO-1994027621-A1 | IRON-BINDING POLYMERS FOR ORAL ADMINISTRATION | GELTEX, INC. (US) | 1994-12-08 | — | — | WO | disclosed |