Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | METAP2 | P50579 | 1/20 | 0.49 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.48 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.48 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.48 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 5/20 | 0.44 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.44 |
| ▸ | PYGL | P06737 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7051160 | 1.00 | MEN1 (0.54) | MEN1KMT2AHPGDMETAP2PLAAT3 | |
| SCHEMBL7619115 | 0.89 | BACE1 (0.51) | MEN1KMT2AATML3MBTL1BACE1 | |
| SCHEMBL7619106 | 0.89 | BACE1 (0.51) | MEN1KMT2AATML3MBTL1BACE1 | |
| SCHEMBL5388616 | 0.86 | KLK5 (0.52) | MEN1KMT2AHPGDMETAP2PLAAT3 | |
| SCHEMBL5388612 | 0.86 | KLK5 (0.52) | MEN1KMT2AHPGDMETAP2PLAAT3 | |
| SCHEMBL7607679 | 0.85 | ALDH1A1 (0.49) | MEN1KMT2AHPGDPLAAT3PLAAT5 | |
| SCHEMBL3348155 | 0.82 | BACE1 (0.54) | BACE1SLC6A11BCHE | |
| SCHEMBL3348148 | 0.82 | BACE1 (0.54) | BACE1SLC6A11BCHE | |
| SCHEMBL3352913 | 0.82 | METAP2 (0.55) | MEN1KMT2AHPGDMETAP2PLAAT3 | |
| Hydrochloric Acid SCHEMBL5217997 | 0.81 | METAP2 (0.54) | MEN1KMT2AHPGDMETAP2PLAAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004502669-A | — | — | 2004-01-29 | — | — | JP | claimed |
| EP-1353898-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2003-10-22 | — | — | EP | claimed |
| WO-2002002512-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |