Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7051771 | 1.00 | ALDH1A1 (0.44) | ALDH1A1ALOX15MAPK1KCNN4ESR1 | |
| SCHEMBL7051770 | 1.00 | ALDH1A1 (0.44) | ALDH1A1ALOX15MAPK1KCNN4ESR1 | |
| SCHEMBL7050025 | 1.00 | ALDH1A1 (0.44) | ALDH1A1ALOX15MAPK1KCNN4ESR1 | |
| SCHEMBL7051369 | 1.00 | ALDH1A1 (0.44) | ALDH1A1ALOX15MAPK1KCNN4ESR1 | |
| SCHEMBL6045469 | 0.83 | KCNN4 (0.32) | ALDH1A1ALOX15KCNN4MDM2 | |
| SCHEMBL6045479 | 0.83 | KCNN4 (0.32) | ALDH1A1ALOX15KCNN4MDM2 | |
| SCHEMBL7047885 | 0.78 | ALDH1A1 (0.40) | ALDH1A1ALOX15MAPK1KCNN4CHRM3 | |
| SCHEMBL7047894 | 0.78 | ALDH1A1 (0.40) | ALDH1A1ALOX15MAPK1KCNN4CHRM3 | |
| SCHEMBL7047888 | 0.78 | ALDH1A1 (0.40) | ALDH1A1ALOX15MAPK1KCNN4CHRM3 | |
| SCHEMBL7052642 | 0.75 | MAPK1 (0.38) | ALDH1A1ALOX15MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086942-B1 | Optically active alcohols and processes for the preparation thereof | CHISSO CORP (JP) | 2003-04-23 | — | — | EP | claimed |
| EP-1086942-A1 | Optically active alcohols and processes for the preparation thereof | CHISSO CORPORATION (JP) | 2001-03-28 | — | — | EP | claimed |
| EP-1086942-B1 | Optically active alcohols and processes for the preparation thereof | CHISSO CORP (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-6495725-B2 | USEFUL AS CHEMICAL INTERMEDIATES FOR PROSTAGLANDINS AND DRUGS | CHISSO CORPORATION (JP) | 2002-12-17 | — | — | US | disclosed |
| US-20020028958-A1 | Process for the preparation of optically active enones and intermediates thereof | JNC CORPORATION (JP) | 2002-03-07 | — | — | US | disclosed |
| JP-2001158758-A | OPTICALLY ACTIVE COMPOUND AND METHOD OF PRODUCING THE SAME | CHISSO CORP | 2001-06-12 | — | — | JP | disclosed |
| EP-1086942-A1 | Optically active alcohols and processes for the preparation thereof | CHISSO CORPORATION (JP) | 2001-03-28 | — | — | EP | disclosed |
| EP-1086942-A1 | Optically active alcohols and processes for the preparation thereof | CHISSO CORPORATION (JP) | 2001-03-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020028958-A1 | Process for the preparation of optically active enones and intermediates thereof | HSD17B7, NR3C2, CYP11B1 | ALDH1A1 471/4885ALOX15 305/4885MAPK1 412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.