Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.49 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.49 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1438861 | 0.87 | PLAU (0.53) | TDP1ALDH1A1CYP3A4TSHRTXNRD1 | |
| SCHEMBL3366468 | 0.81 | MAPT (0.50) | TDP1ALDH1A1CYP3A4MAPTTSHR | |
| SCHEMBL28753879 | 0.79 | MAPT (0.51) | TDP1ALDH1A1CYP3A4MAPTTSHR | |
| SCHEMBL30918562 | 0.78 | MAPT (0.50) | TDP1ALDH1A1CYP3A4MAPTTSHR | |
| SCHEMBL28046316 | 0.78 | MAPT (0.50) | TDP1ALDH1A1CYP3A4MAPTTSHR | |
| SCHEMBL28046337 | 0.78 | MAPT (0.50) | TDP1ALDH1A1CYP3A4MAPTTSHR | |
| SCHEMBL8892090 | 0.77 | ALDH1A1 (0.50) | TDP1ALDH1A1CYP3A4TSHRGAA | |
| SCHEMBL19144359 | 0.76 | TDP1 (0.56) | TDP1ALDH1A1CYP3A4MAPTTSHR | |
| SCHEMBL31473179 | 0.75 | MEN1 (0.52) | TDP1ALDH1A1CYP3A4MAPTTSHR | |
| SCHEMBL17154408 | 0.74 | ACHE (0.64) | TDP1ALDH1A1CYP3A4MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003013523-A1 | SH3 PROTEIN DOMAINS AND THEIR LIGANDS | ADELAIDE RESEARCH & INNOVATION PTY LTD (AU) | 2003-02-20 | — | — | WO | claimed |
| WO-2003013523-A1 | SH3 PROTEIN DOMAINS AND THEIR LIGANDS | ADELAIDE RESEARCH & INNOVATION PTY LTD (AU) | 2003-02-20 | — | — | WO | disclosed |