Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL704878 | 0.84 | GABRA1 (0.33) | GABRA1GABRB2MEN1MAPTMAPK1 | |
| SCHEMBL2536793 | 0.81 | GABRA1 (0.36) | GABRA1GABRB2 | |
| SCHEMBL3334611 | 0.76 | TAAR1 (0.30) | — | |
| SCHEMBL5822189 | 0.76 | GABRA1 (0.50) | GABRA1GABRB2MEN1MAPTKMT2A | |
| SCHEMBL6594676 | 0.76 | GABRA1 (0.33) | GABRA1GABRB2 | |
| SCHEMBL28130205 | 0.74 | — | — | |
| SCHEMBL3644895 | 0.73 | GABRA1 (0.32) | GABRA1GABRB2 | |
| SCHEMBL458616 | 0.72 | — | — | |
| SCHEMBL27343129 | 0.72 | — | — | |
| SCHEMBL17894914 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6683092-B1 | BREAST AND/OR PROSTATE CANCER | ALLERGAN, INC. | 2004-01-27 | — | — | US | disclosed |