Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NAAA | Q02083 | 2/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.35 |
| ▸ | PAM | P19021 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7060615 | 1.00 | DGKA (0.41) | DGKAEPHX2PRSS1PRSS2PRSS3 | |
| SCHEMBL7059512 | 0.92 | SMN1; SMN2 (0.39) | DGKAEPHX2ALDH1A1TSHR | |
| SCHEMBL7052861 | 0.84 | ALDH1A1 (0.40) | ALDH1A1TSHR | |
| SCHEMBL7060130 | 0.81 | ALDH1A1 (0.55) | DGKAPRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL7058911 | 0.81 | ALDH1A1 (0.55) | DGKAPRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL7759962 | 0.80 | DGKA (0.57) | DGKACES2ALDH1A1TSHRLMNA | |
| SCHEMBL11616036 | 0.80 | DGKA (0.47) | DGKAEPHX2PRSS1PRSS2PRSS3 | |
| SCHEMBL20210561 | 0.79 | TSHR (0.56) | DGKAEPHX2ALDH1A1TSHRLMNA | |
| SCHEMBL20210610 | 0.79 | DGKA (0.55) | DGKAEPHX2PRSS1PRSS2PRSS3 | |
| SCHEMBL3827295 | 0.79 | DGKA (0.55) | DGKAEPHX2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1006118-B1 | Method for synthesizing organosilicon compounds that contain a group bonded to silicon across the SI-C bond | DOW CORNING ASIA LTD (JP) | 2003-05-07 | — | — | EP | disclosed |
| US-6175031-B1 | PLATINUM-CATALYZED HYDROSILYLATION BETWEEN SIH-SUBSTITUTED SILICON COMPOUNDS AND UNSATURATED GROUP-FUNCTIONAL ORGANIC OR ORGANOSILICON COMPOUNDS IN PRESENCE OF A (ACYLOXY)-FUNCTIONAL HYDROGENSILANE COMPOUND OR ACID AND HYDRO(ALKOXY)SILANE | DOW CORNING ASIA, LTD. (JP) | 2001-01-16 | — | — | US | disclosed |
| US-6111126-A | Method for synthesizing organosilicon compounds that contain a functional group bonded to silicon across the Si-C bond | DOW CORNING ASIA, LTD. (JP) | 2000-08-29 | — | — | US | disclosed |
| EP-1006118-A2 | Method for synthesizing organosilicon compounds that contain a group bonded to silicon across the SI-C bond | Dow Corning Asia, Ltd. (JP) | 2000-06-07 | — | — | EP | disclosed |