SCHEMBL7051745

SCHEMBL7051745

[NH]Cc1ccc(S(=O)(=O)C(F)(F)F)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPRZ1 P23471 1/20 0.58
LMNA P02545 3/20 0.46
HTT P42858 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
MAPK1 P28482 1/20 0.46
ALDH1A1 P00352 1/20 0.46
KIF11 P52732 2/20 0.43
CA2 P00918 4/20 0.40
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
CA1 P00915 2/20 0.38
ESPL1 Q14674 1/20 0.38
MBOAT4 Q96T53 1/20 0.37
NAMPT P43490 1/20 0.37
TEAD1 P28347 1/20 0.36
BCHE P06276 1/20 0.36
ACHE P22303 1/20 0.36
POLB P06746 1/20 0.36
EPAS1 Q99814 1/20 0.35
PSEN1 P49768 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6001716 0.83 PTPRZ1 (0.61) PTPRZ1LMNAHTTSMN1; SMN2MAPK1
SCHEMBL7050691 0.81 PTPRZ1 (0.59) PTPRZ1LMNAHTTSMN1; SMN2MAPK1
SCHEMBL718482 0.79 PTPRZ1 (0.58) PTPRZ1LMNAHTTSMN1; SMN2MAPK1
SCHEMBL1145752 0.79 PTPRZ1 (0.58) PTPRZ1LMNAHTTSMN1; SMN2MAPK1
SCHEMBL10181461 0.79 PTPRZ1 (0.58) PTPRZ1LMNAHTTSMN1; SMN2MAPK1
SCHEMBL25467365 0.79 PTPRZ1 (0.58) PTPRZ1LMNAHTTSMN1; SMN2MAPK1
SCHEMBL1099385 0.79 PTPRZ1 (0.58) PTPRZ1LMNAHTTSMN1; SMN2MAPK1
Hydrochloric Acid SCHEMBL1857101 0.78 CA2 (0.59) PTPRZ1LMNAHTTSMN1; SMN2MAPK1
SCHEMBL6001722 0.78 PTPRZ1 (0.71) PTPRZ1LMNAHTTSMN1; SMN2MAPK1
SCHEMBL7053871 0.77 ALDH1A1 (0.44) PTPRZ1LMNAHTTSMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0882715-B1 NOVEL N-(UNSUBSTITUTED OR SUBSTITUTED)-4-SUBSTITUTED-6-(UNSUBSTITUTED OR SUBSTITUTED)PHENOXY-2-PYRIDINECARBOXAMIDES OR THIOCARBOXAMIDES, PROCESSES FOR PRODUCING THE SAME, AND HERBICIDES KUREHA CHEMICAL IND CO LTD (JP) 2003-04-23 EP disclosed
US-6339045-B1 CAN BE USED IN A SMALL AMOUNT, SHOWING A GOOD SELECTIVITY BETWEEN CROP AND WEED, AND CAUSING NO PHYTOTOXICITY KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2002-01-15 US disclosed
EP-0882715-A1 NOVEL N-(UNSUBSTITUTED OR SUBSTITUTED)-4-SUBSTITUTED-6-(UNSUBSTITUTED OR SUBSTITUTED)PHENOXY-2-PYRIDINECARBOXAMIDES OR THIOCARBOXAMIDES, PROCESSES FOR PRODUCING THE SAME, AND HERBICIDES KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1998-12-09 EP disclosed