SCHEMBL7052011

SCHEMBL7052011

O=C1CN(S(=O)(=O)c2ccc3cc(Cl)ccc3c2)CCN1CC1(O)CCN(c2cc(NCc3ccccc3)ncn2)CC1

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
METTL3 Q86U44 7/20 0.42
PIK3CB P42338 1/20 0.42
HRH4 Q9H3N8 1/20 0.42
F10 P00742 8/20 0.38
MAPK8 P45983 1/20 0.38
TP53 P04637 1/20 0.38
MAPT P10636 1/20 0.38
F2 P00734 1/20 0.38
METTL14 Q9HCE5 1/20 0.37
PRCP P42785 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7053479 0.86 F10 (0.43) F10F2
SCHEMBL7048671 0.82 F10 (0.49) F10F2
SCHEMBL7052225 0.80 F10 (0.46) F10F2
SCHEMBL7054073 0.77 F10 (0.60) F10
Hydrochloric Acid SCHEMBL7735991 0.76 F10 (0.59) F10
SCHEMBL7052015 0.76 F10 (0.37) F10TP53MAPTF2
SCHEMBL7112065 0.76 F10 (0.48) F10
Hydrochloric Acid SCHEMBL7049914 0.74 F10 (0.44) F10MAPTF2
Hydrochloric Acid SCHEMBL6888185 0.74 HRH4 (0.51) METTL3PIK3CBHRH4MAPK8METTL14
Hydrochloric Acid SCHEMBL7050218 0.73 F10 (0.41) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6680312-B2 FOR THERAPY OF CARDIAC INFARCTION, CEREBRAL THROMBOSIS; INHIBIT ACTIVATED COAGULATION FACTOR X (FXA) TO SHOW ANTI-COAGULANT ACTIVITY TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2004-01-20 US disclosed
US-20020193382-A1 Sulfonamide derivatives, their production and use TAKEDA PHARMACEUTICAL COMPANY, LIMITED (JP) 2002-12-19 US disclosed
US-6403595-B1 ANTICOAGULANTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2002-06-11 US disclosed
EP-1054005-A1 SULFONAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND UTILIZATION THEREOF Takeda Chemical Industries, Ltd. (JP) 2000-11-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020193382-A1 Sulfonamide derivatives, their production and use F12, F11, F2 METTL3 3303/4885PIK3CB 3631/4885HRH4 224/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.