Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 10/20 | 0.34 |
| ▸ | HTR2A | P28223 | 6/20 | 0.34 |
| ▸ | HTR2B | P41595 | 4/20 | 0.34 |
| ▸ | HTR1A | P08908 | 3/20 | 0.34 |
| ▸ | HTR1D | P28221 | 3/20 | 0.34 |
| ▸ | HTR7 | P34969 | 3/20 | 0.34 |
| ▸ | HTR5A | P47898 | 3/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11465484 | 0.79 | GSTO1 (0.34) | GSTO1HTR2CHTR1AHTR1DHTR7 | |
| SCHEMBL4319533 | 0.78 | SMN1; SMN2 (0.43) | TSHRHTR2CHTR2AHTR2BHTR1A | |
| SCHEMBL7053925 | 0.78 | CYP3A4 (0.41) | TSHRGSTO1CYP3A4MAPK1AHR | |
| SCHEMBL4317902 | 0.78 | SMN1; SMN2 (0.43) | TSHRHTR2CHTR2AHTR2BHTR1A | |
| SCHEMBL7054472 | 0.74 | CYP3A4 (0.36) | TSHRGSTO1HTR2CHTR2AHTR2B | |
| SCHEMBL7052010 | 0.74 | CYP3A4 (0.43) | TSHRGSTO1CYP3A4MAPK1AHR | |
| SCHEMBL7050740 | 0.71 | TSHR (0.32) | TSHR | |
| SCHEMBL1943987 | 0.70 | SMARCA2 (0.45) | MAPK1 | |
| SCHEMBL11262128 | 0.70 | — | — | |
| SCHEMBL13706924 | 0.70 | SMARCA2 (0.45) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611826-B1 | Processes for production of optically active epoxides | DAICEL CHEM (JP) | 2003-05-02 | — | — | EP | disclosed |
| US-5672504-A | TREATING MIXED EPOXIDE ENANTIOMORPHS WITH MICROORGANISMS TO INCREASE CONCENTRATION OF OPTICALLY PURE S-ENANTIOMORPHS | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1997-09-30 | — | — | US | disclosed |
| EP-0611826-A2 | Processes for production of optically active epoxides | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1994-08-24 | — | — | EP | disclosed |