Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 6/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.31 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7053925 | 0.86 | CYP3A4 (0.41) | CYP3A4TSHRHPGDHSD17B10MAPK1 | |
| SCHEMBL7053304 | 0.76 | ALDH1A1 (0.39) | CYP3A4TSHRHPGDHSD17B10AHR | |
| SCHEMBL7050740 | 0.75 | TSHR (0.32) | TSHR | |
| SCHEMBL7052026 | 0.74 | TSHR (0.36) | CYP3A4TSHRMAPK1AHRGSTO1 | |
| SCHEMBL7054788 | 0.73 | CYP3A4 (0.43) | CYP3A4TSHRHPGDHSD17B10MAPK1 | |
| SCHEMBL7053649 | 0.71 | TSHR (0.42) | CYP3A4TSHRHPGDHSD17B10AHR | |
| SCHEMBL11262128 | 0.68 | — | — | |
| SCHEMBL19688664 | 0.68 | TSHR (0.30) | TSHR | |
| SCHEMBL4317902 | 0.67 | SMN1; SMN2 (0.43) | TSHRHPGDHSD17B10AHRCASP1 | |
| SCHEMBL7050638 | 0.67 | TSHR (0.37) | TSHRHPGDHSD17B10MAPK1AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611826-B1 | Processes for production of optically active epoxides | DAICEL CHEM (JP) | 2003-05-02 | — | — | EP | disclosed |
| US-5672504-A | TREATING MIXED EPOXIDE ENANTIOMORPHS WITH MICROORGANISMS TO INCREASE CONCENTRATION OF OPTICALLY PURE S-ENANTIOMORPHS | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1997-09-30 | — | — | US | disclosed |
| EP-0611826-A2 | Processes for production of optically active epoxides | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1994-08-24 | — | — | EP | disclosed |