SCHEMBL705203

SCHEMBL705203

Cl[Si](Cl)(CCCC[Si](Cl)(Cl)c1ccccc1)c1ccccc1

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.31
TSHR P16473 1/20 0.30
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30
KCNH2 Q12809 1/20 0.30
CYP19A1 P11511 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL703162 0.95 MAPT (0.31) MAPTTSHRESR1ESR2CYP19A1
SCHEMBL706034 0.89 TSHR (0.33) TSHRESR1ESR2CYP19A1
SCHEMBL11578304 0.89 SLC9A1 (0.30)
SCHEMBL975134 0.89 KCNH2 (0.39) TSHRKCNH2CYP19A1
SCHEMBL4271660 0.88 SLC9A1 (0.32)
SCHEMBL2101335 0.87 KCNH2 (0.42) KCNH2CYP19A1
SCHEMBL29199583 0.87 KCNH2 (0.42) KCNH2CYP19A1
SCHEMBL20483303 0.87 KCNH2 (0.42) KCNH2CYP19A1
SCHEMBL20483516 0.87 KCNH2 (0.42) KCNH2CYP19A1
SCHEMBL19470853 0.87 KCNH2 (0.42) KCNH2CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8124239-B2 Silica film forming material, silica film and method of manufacturing the same, multilayer wiring structure and method of manufacturing the same, and semiconductor device and method of manufacturing the same FUJITSU LIMITED (JP) 2012-02-28 US disclosed
US-20100155121-A1 SILICA FILM FORMING MATERIAL, SILICA FILM AND METHOD OF MANUFACTURING THE SAME, MULTILAYER WIRING STRUCTURE AND METHOD OF MANUFACTURING THE SAME, AND SEMICONDUCTOR DEVICE AND METHOD OF MANUFACTURING THE SAME FUJITSU LIMITED (JP) 2010-06-24 US disclosed
US-7659357-B2 Precursor organosilicon polymer of 1,2-Bis(dimethylethoxysilyl)ethane, 1,4-bis(dimethylethoxysilyl)benzene, tetraethoxysilane, methyltriethoxysilane, phenyltriethoxysilane; dielectric (DE) films having etching/chemical/moisture resistance; adhesion; low DE constant; minimal wiring delay; high speed FUJITSU LIMITED (JP) 2010-02-09 US disclosed
US-20070026689-A1 Silica film forming material, silica film and method of manufacturing the same, multilayer wiring structure and method of manufacturing the same, and semiconductor device and method of manufacturing the same FUJITSU LIMITED (JP) 2007-02-01 US disclosed