Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTTP | P55157 | 8/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | MTR | Q99707 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7049652 | 0.84 | MTTP (0.51) | MTTPCHRM2ADRA2AADORA3CHRM1 | |
| SCHEMBL7051640 | 0.84 | MTTP (0.51) | MTTPCHRM2ADRA2AADORA3CHRM1 | |
| SCHEMBL6771834 | 0.77 | MTTP (0.60) | MTTPCHRM2ADRA2AADORA3CHRM1 | |
| SCHEMBL7051125 | 0.76 | MTTP (0.46) | MTTPCHRM2ADRA2AADORA3CHRM1 | |
| SCHEMBL7048287 | 0.75 | MTTP (0.54) | MTTPCHRM2ADRA2AADORA3CHRM1 | |
| SCHEMBL7049994 | 0.74 | MTTP (0.57) | MTTPCHRM2ADRA2AADORA3CHRM1 | |
| SCHEMBL23646035 | 0.73 | ALDH1A1 (0.37) | — | |
| SCHEMBL7596509 | 0.72 | MTTP (0.61) | MTTPCHRM2ADRA2AADORA3CHRM1 | |
| SCHEMBL17742237 | 0.72 | MTTP (0.67) | MTTPCHRM2ADRA2AADORA3CHRM1 | |
| SCHEMBL6792901 | 0.72 | MTTP (0.57) | MTTPCHRM2ADRA2AADORA3CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030114442-A1 | Substituted piperazine derivatives as mtp inhibitors | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2003-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030114442-A1 | Substituted piperazine derivatives as mtp inhibitors | MTTP, CETP, LIPC | MTTP 1/4885CHRM2 4129/4885ADRA2A 966/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.