Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8835612 | 0.79 | PDE2A (0.52) | KMT2ALMNACYP1A2PDE2APOLB | |
| SCHEMBL29450819 | 0.78 | PDE2A (0.55) | KMT2ALMNAMAPTGAACYP1A2 | |
| SCHEMBL7052100 | 0.78 | PDE2A (0.55) | KMT2ALMNAMAPTGAACYP1A2 | |
| SCHEMBL1880465 | 0.77 | NUDT1 (0.55) | MAPTGAACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6970113 | 0.74 | ALDH1A1 (0.51) | KMT2AMAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL13012202 | 0.73 | SMN1; SMN2 (0.50) | KMT2ALMNAMAPTGAACYP1A2 | |
| SCHEMBL17194885 | 0.73 | MAPT (0.50) | KMT2ALMNAMAPTGAACYP1A2 | |
| SCHEMBL196024 | 0.73 | — | — | |
| SCHEMBL24589999 | 0.71 | KMT2A (0.42) | KMT2ALMNAMAPTGAACYP1A2 | |
| Water SCHEMBL6010194 | 0.70 | POLB (0.50) | KMT2ALMNAMAPTGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1304325-A1 | 5-(M-CYANOBENZYLAMINO)PYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-04-23 | — | — | EP | disclosed |