Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL1 | P55085 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 6/20 | 0.38 |
| ▸ | METAP2 | P50579 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 4/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6179554 | 0.78 | METAP1 (0.46) | F2RL1METAP1METAP2KDM4ENPC1 | |
| SCHEMBL27850713 | 0.73 | NISCH (0.39) | KDM4ECYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL3684945 | 0.69 | F2RL1 (0.49) | F2RL1METAP1METAP2KDM4ENPC1 | |
| SCHEMBL2647072 | 0.68 | BACE1 (0.40) | KDM4ENPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL23815521 | 0.63 | NISCH (0.41) | KDM4ECYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL27687541 | 0.61 | NISCH (0.42) | KDM4ENPC1TP53CYP1A2CYP3A4 | |
| SCHEMBL4993051 | 0.61 | ADRA2A (0.41) | F2RL1KDM4ESMN1; SMN2NISCHMTOR | |
| SCHEMBL7964249 | 0.60 | TSHR (0.50) | METAP1METAP2KDM4ENPC1TP53 | |
| SCHEMBL81650 | 0.60 | NISCH (0.59) | KDM4ECYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL31412321 | 0.60 | GSK3B (0.41) | KDM4ENPC1RAB9ASMN1; SMN2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003022219-A2 | BIARYLAMINO PURINE ANTIPROLIFERATIVE AGENTS | ALBANY MOLECULAR RESEARCH, INC. (US) | 2003-03-20 | — | — | WO | claimed |