SCHEMBL7052254

SCHEMBL7052254

Cc1cccc([Si](C2=CC=CC2)(c2ccccc2)c2ccccc2)c1

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.34
NPSR1 Q6W5P4 1/20 0.33
TSHR P16473 2/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
HPGD P15428 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
LMNA P02545 1/20 0.31
ALOX12 P18054 1/20 0.31
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7056345 0.86 ESR1 (0.30)
SCHEMBL7055426 0.82 ESR1 (0.30)
SCHEMBL4651356 0.82 ESR1 (0.30)
SCHEMBL9143092 0.81
SCHEMBL9144796 0.81
SCHEMBL4546863 0.78 ACHE (0.50) ACHENPSR1TSHRNPC1RAB9A
SCHEMBL2454956 0.78 ACHE (0.50) ACHENPSR1TSHRNPC1RAB9A
SCHEMBL2454749 0.78 ACHE (0.50) ACHENPSR1TSHRNPC1RAB9A
SCHEMBL29265257 0.77 ACHE (0.48) ACHENPSR1TSHRNPC1RAB9A
SCHEMBL10317201 0.76 ACHE (0.33) ACHENPSR1TSHRNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0985674-B1 ORGANIC COMPOUNDS CONTAINING SILICON OR GERMANIUM, TRANSITION METAL COMPLEXES, CATALYST FOR ALPHA-OLEFIN POLYMERIZATION, AND PROCESSES FOR PRODUCING ALPHA-OLEFIN POLYMERS MITSUBISHI CHEM CORP (JP) 2003-04-23 EP disclosed
US-6255515-B1 COORDINATION POLYMERIZATION CATALYSTS MITSUBISHI CHEMICAL CORPORATION (JP) 2001-07-03 US disclosed
EP-0985674-A1 ORGANIC COMPOUNDS CONTAINING SILICON OR GERMANIUM, TRANSITION METAL COMPLEXES, CATALYST FOR $g(a)-OLEFIN POLYMERIZATION, AND PROCESSES FOR PRODUCING $g(a)-OLEFIN POLYMERS MITSUBISHI CHEMICAL CORPORATION (JP) 2000-03-15 EP disclosed