Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 3/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 3/20 | 0.33 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.33 |
| ▸ | UCHL3 | P15374 | 2/20 | 0.33 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.33 |
| ▸ | CDK1 | P06493 | 2/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.33 |
| ▸ | GSK3A | P49840 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 2/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.33 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.32 |
| ▸ | AURKC | Q9UQB9 | 2/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7053388 | 0.89 | CES1 (0.44) | CES1BCHETGM2UCHL1UCHL3 | |
| SCHEMBL7055737 | 0.86 | CES1 (0.38) | CES1BCHETGM2CCNB2CDK1 | |
| SCHEMBL7054757 | 0.83 | CES1 (0.53) | CES1BCHETGM2UCHL1UCHL3 | |
| SCHEMBL7049532 | 0.81 | KMT2A (0.43) | CES1BCHECCNB2CDK1CCNB1 | |
| SCHEMBL7050076 | 0.77 | CES1 (0.49) | CES1BCHETGM2CA12CA1 | |
| SCHEMBL7050072 | 0.77 | CES1 (0.49) | CES1BCHETGM2CA12CA1 | |
| SCHEMBL7055054 | 0.77 | KMT2A (0.50) | TGM2SMN1; SMN2AGTR1MEN1NPC1 | |
| SCHEMBL7052536 | 0.77 | TGM2 (0.33) | CES1TGM2 | |
| SCHEMBL7052986 | 0.76 | CES1 (0.38) | CES1TGM2UCHL1UCHL3CCNB2 | |
| SCHEMBL7053093 | 0.76 | CES1 (0.38) | CES1BCHETGM2CCNB2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0706396-B1 | 1,2,3,4-TETRAHYDROQUINOLINE-2,3,4-TRIONE-3 OR 4-OXIMES AND USE | OREGON STATE (US) | 2003-05-02 | — | — | EP | disclosed |
| US-5652368-A | NERVOUS SYSTEM DISORDERS, ALZHEIMER'S DISEASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-07-29 | — | — | US | disclosed |
| US-5475007-A | Preventing convulsions | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1995-12-12 | — | — | US | disclosed |