SCHEMBL7052326

SCHEMBL7052326

C=C(CCS(=O)(=O)CC)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 1/20 0.42
TET2 Q6N021 4/20 0.34
TET3 O43151 1/20 0.32
TET1 Q8NFU7 1/20 0.32
KMT2A Q03164 1/20 0.32
LMNA P02545 1/20 0.31
GRIK1 P39086 1/20 0.31
GRIK2 Q13002 1/20 0.31
GRM1 Q13255 1/20 0.31
GRM2 Q14416 1/20 0.31
ALOX15 P16050 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL184599 0.87 TBXAS1 (0.37) APEX1TET2TET3TET1
SCHEMBL6030920 0.79 TET2 (0.35) APEX1TET2TET3TET1GRIK1
SCHEMBL165516 0.76 PTGS1 (0.36) APEX1TET2TET3TET1LMNA
SCHEMBL7131000 0.75 APEX1 (0.74) APEX1KMT2ALMNAALOX15HSD17B10
SCHEMBL9574731 0.74 PTGS1 (0.35) APEX1TET2TET3TET1LMNA
Ammonia Solution, Strong SCHEMBL5052690 0.74 PTGS1 (0.35) APEX1TET2TET3TET1LMNA
SCHEMBL22092733 0.74 ALOX15 (0.33) APEX1TET2TET3TET1ALOX15
Hydrochloric Acid SCHEMBL10583773 0.73 APEX1 (0.70) APEX1KMT2ALMNAALOX15HSD17B10
SCHEMBL17818 0.72
SCHEMBL21986236 0.71 TBXAS1 (0.38) APEX1TET2TET3TET1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003048176-A1 CATALYST FOR PRODUCING (CO)POLYMERS OF (METH)ACRYLIC COMPOUNDS Röhm GmbH & Co. KG (DE) 2003-06-12 WO disclosed
WO-2003029310-A1 METHOD AND DEVICE FOR PRODUCING A HIGHLY MOLECULAR POLY(METH)ACRYLATE RÖHM GBMH & CO.KG (DE) 2003-04-10 WO disclosed