SCHEMBL7052585

SCHEMBL7052585

CN(C)c1ccc(-c2ccc(F)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 6/20 0.64
ALDH1A1 P00352 6/20 0.58
ALOX15 P16050 5/20 0.58
HSD17B10 Q99714 3/20 0.58
TSHR P16473 2/20 0.58
MAPT P10636 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
MAPK1 P28482 5/20 0.47
CYP3A4 P08684 4/20 0.47
USP2 O75604 3/20 0.47
CYP1A2 P05177 3/20 0.47
CYP2D6 P10635 3/20 0.47
CYP2C19 P33261 3/20 0.47
CLK4 Q9HAZ1 3/20 0.47
TP53 P04637 3/20 0.47
MEN1 O00255 2/20 0.47
CYP2C9 P11712 2/20 0.47
KMT2A Q03164 2/20 0.47
GLA P06280 1/20 0.47
LMNA P02545 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL59001 0.92 APP (0.73) APPALDH1A1ALOX15HSD17B10TSHR
Ethyne SCHEMBL9049731 0.86 APP (0.67) APPALDH1A1ALOX15HSD17B10TSHR
SCHEMBL11547412 0.86 ALDH1A1 (0.79) APPALDH1A1ALOX15HSD17B10TSHR
SCHEMBL124209 0.86 ALDH1A1 (0.79) APPALDH1A1ALOX15HSD17B10TSHR
Cyclopropane SCHEMBL28538522 0.84 APP (0.64) APPALDH1A1ALOX15HSD17B10TSHR
Hydrochloric Acid SCHEMBL30448295 0.83 ALDH1A1 (0.73) APPALDH1A1ALOX15HSD17B10TSHR
Hydrochloric Acid SCHEMBL31707017 0.83 ALDH1A1 (0.73) APPALDH1A1ALOX15HSD17B10TSHR
SCHEMBL8617554 0.82 APP (0.53) APPALDH1A1ALOX15HSD17B10MAPT
SCHEMBL10415424 0.82 APP (0.53) APPALDH1A1ALOX15HSD17B10MAPT
Hydrochloric Acid SCHEMBL31597062 0.80 ALDH1A1 (0.69) APPALDH1A1ALOX15HSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1301577-A2 COLORLESS AND LOW VISCOSITY COMPOUNDS FOR LOW VOLTAGE LIQUID CRYSTAL OPERATION Raytheon Company (US) 2003-04-16 EP disclosed
US-6468443-B1 DOPANT CHOSEN FROM FLUORINATED AMINO BIPHENYL, CONJUGATED DIACETYLENE AMINO DIPHENYL AND NONCONJUGATED DIACETYLENE AMINO TRIPHENYL COMPOUNDS; LARGE DIELECTRIC ANISOTROPY; RETAINING FAST RESPONSE TIME RAYTHEON COMPANY 2002-10-22 US disclosed
WO-2002008356-A2 COLORLESS AND LOW VISCOSITY COMPOUNDS FOR LOW VOLTAGE LIQUID CRYSTAL OPERATION RAYTHEON COMPANY (US) 2002-01-31 WO disclosed