Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | MPO | P05164 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | KDM4A | O75164 | 2/20 | 0.43 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL59001 | 0.92 | APP (0.73) | APPALDH1A1TSHRALOX15HSD17B10 | |
| Ethyne SCHEMBL9049731 | 0.86 | APP (0.67) | APPALDH1A1TSHRALOX15HSD17B10 | |
| Cyclopropane SCHEMBL7686540 | 0.84 | APP (0.46) | APPALDH1A1TSHRALOX15HSD17B10 | |
| SCHEMBL7052585 | 0.84 | APP (0.64) | APPALDH1A1TSHRALOX15HSD17B10 | |
| SCHEMBL4265855 | 0.80 | APP (0.59) | APPALDH1A1TSHRALOX15HSD17B10 | |
| Phosphoric Acid SCHEMBL10591537 | 0.78 | APP (0.57) | APPALDH1A1TSHRALOX15HSD17B10 | |
| SCHEMBL5982603 | 0.78 | NPC1 (0.67) | APPALDH1A1TSHRALOX15HSD17B10 | |
| Phosphonic Acid SCHEMBL10591908 | 0.78 | APP (0.57) | APPALDH1A1TSHRALOX15HSD17B10 | |
| SCHEMBL6117396 | 0.78 | APP (0.57) | APPALDH1A1TSHRALOX15HSD17B10 | |
| SCHEMBL12069735 | 0.78 | NPC1 (0.67) | APPALDH1A1TSHRALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112390749-A | Synthesis method of cabozantinib and intermediate thereof | 鲁南制药集团股份有限公司 | 2021-02-23 | — | — | CN | disclosed |