Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7055896 | 0.89 | KMT2A (0.50) | KMT2AALDH1A1HPGDF2ATM | |
| SCHEMBL7049532 | 0.83 | KMT2A (0.43) | KMT2AALDH1A1HPGDF2ATM | |
| SCHEMBL7051552 | 0.83 | CES1 (0.47) | KMT2AALDH1A1HPGDF2ATM | |
| SCHEMBL7055054 | 0.83 | KMT2A (0.50) | KMT2AALDH1A1MAOAMAOBMAPT | |
| SCHEMBL10624339 | 0.79 | ALDH1A1 (0.57) | KMT2AALDH1A1HPGDF2ATM | |
| SCHEMBL7054941 | 0.78 | KMT2A (0.38) | KMT2AALDH1A1HPGDF2ATM | |
| SCHEMBL7051548 | 0.77 | CES1 (0.48) | KMT2AALDH1A1HPGDF2ATM | |
| SCHEMBL7054751 | 0.77 | KMT2A (0.38) | KMT2AALDH1A1HPGDF2ATM | |
| SCHEMBL7050457 | 0.77 | KMT2A (0.38) | KMT2AALDH1A1HPGDF2ATM | |
| SCHEMBL7052934 | 0.76 | KMT2A (0.41) | KMT2AALDH1A1HPGDF2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0706396-B1 | 1,2,3,4-TETRAHYDROQUINOLINE-2,3,4-TRIONE-3 OR 4-OXIMES AND USE | OREGON STATE (US) | 2003-05-02 | — | — | EP | disclosed |
| US-5475007-A | Preventing convulsions | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1995-12-12 | — | — | US | disclosed |