Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL247231 | 0.91 | TSHR (0.50) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL21811060 | 0.89 | TSHR (0.49) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL5701761 | 0.84 | TSHR (0.46) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL2502772 | 0.83 | THRB (0.54) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL5701781 | 0.81 | TSHR (0.47) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL10934218 | 0.81 | TSHR (0.44) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL2138102 | 0.81 | THRB (0.51) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL14278963 | 0.81 | THRB (0.51) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL2803513 | 0.81 | THRB (0.60) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL16750970 | 0.80 | THRB (0.58) | THRBTSHRPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1072602-B1 | Carbosiloxane dendrimer and copolymers made therewith | DOW CORNING TORAY SILICONE (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-6306992-B1 | Carbosiloxane dendrimer and dendrimer-containing organic polymers | DOW CORNING TORAY SILICONE COMPANY, LTD. (JP) | 2001-10-23 | — | — | US | disclosed |
| EP-1072602-A1 | Carbosiloxane dendrimer and copolymers made therewith | Dow Corning Toray Silicone Co., Ltd. (JP) | 2001-01-31 | — | — | EP | disclosed |