Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7049975 | 0.96 | PDE5A (0.39) | PDE5AMET | |
| SCHEMBL7051114 | 0.96 | PDE5A (0.34) | PDE5A | |
| SCHEMBL7050684 | 0.95 | KMT2A (0.34) | PDE5AMET | |
| SCHEMBL7050993 | 0.93 | KMT2A (0.34) | PDE5AMET | |
| SCHEMBL7053105 | 0.92 | PDE5A (0.34) | PDE5A | |
| SCHEMBL7053059 | 0.91 | KMT2A (0.38) | PDE5A | |
| SCHEMBL7053379 | 0.91 | PDE5A (0.36) | PDE5AMET | |
| SCHEMBL7056316 | 0.89 | KMT2A (0.35) | PDE5AMET | |
| SCHEMBL6641264 | 0.87 | PDE5A (0.43) | PDE5AMET | |
| SCHEMBL7053575 | 0.87 | KMT2A (0.32) | PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030171361-A1 | Pyrrolopyrimidinone derivatives, process of preparation and use | SK CHEMICALS CO., LTD. (KR) | 2003-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030171361-A1 | Pyrrolopyrimidinone derivatives, process of preparation and use | CYP2C19, DHPS, SDHA | PDE5A 686/4885MET 4109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.