Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CLK1 | P49759 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8183536 | 0.84 | CYP1A2 (0.43) | MEN1KMT2AALDH1A1 | |
| SCHEMBL7253915 | 0.71 | CYP1A2 (0.41) | ALDH1A1 | |
| SCHEMBL27633285 | 0.69 | MEN1 (0.45) | ATRMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL3595004 | 0.68 | ATR (0.37) | ATRMEN1KMT2ALCKPOLB | |
| SCHEMBL7833634 | 0.67 | KDM4E (0.66) | MEN1KMT2ANPSR1GAAALDH1A1 | |
| SCHEMBL17728891 | 0.66 | KDM4E (0.34) | ATRMEN1KMT2ANPSR1GAA | |
| SCHEMBL27537751 | 0.65 | LCK (0.44) | ATRMEN1KMT2ALCKGAA | |
| SCHEMBL17528554 | 0.65 | LCK (0.50) | ATRLCKCA1 | |
| SCHEMBL7006468 | 0.65 | ATR (0.40) | ATRPOLBGAAALDH1A1RAB9A | |
| SCHEMBL5675826 | 0.65 | BRD9 (0.37) | NPC1RAB9AMAPTCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003020877-A2 | STAINING AND SORTING GENOMES AND CHROMOSOMES USING SEQUENCE-SPECIFIC POLYAMIDES | PHARMACIA CORPORATION (US) | 2003-03-13 | — | — | WO | disclosed |
| WO-2002004417-A1 | PROCESS FOR THE PREPARATION OF DERIVATIVES OF 4-AMINO-3-HYDROXYPYRROLE-2-CARBOXYLIC ACID | PHARMACIA CORPORAION (US) | 2002-01-17 | — | — | WO | disclosed |