Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.64 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | POLA1 | P09884 | 1/20 | 0.46 |
| ▸ | DGKA | P23743 | 1/20 | 0.45 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7051236 | 0.98 | CES2 (0.61) | CES2NAAAEPHX1MEN1THRB | |
| SCHEMBL1059079 | 0.91 | CES2 (0.52) | CES2NAAAMEN1KMT2AMAPT | |
| SCHEMBL5050936 | 0.88 | CES2 (0.48) | CES2MEN1THRBHTTKMT2A | |
| SCHEMBL9298686 | 0.83 | NAAA (0.67) | CES2NAAAEPHX1MEN1THRB | |
| SCHEMBL29084475 | 0.83 | GAA (0.47) | CES2MEN1THRBHTTKMT2A | |
| SCHEMBL27749473 | 0.83 | NAAA (0.67) | CES2NAAAEPHX1MEN1THRB | |
| SCHEMBL8511737 | 0.83 | NAAA (0.67) | CES2NAAAEPHX1MEN1THRB | |
| SCHEMBL9766323 | 0.83 | NAAA (0.67) | CES2NAAAEPHX1MEN1THRB | |
| SCHEMBL9766365 | 0.83 | NAAA (0.67) | CES2NAAAEPHX1MEN1THRB | |
| 1-Pentanol SCHEMBL28223190 | 0.82 | MEN1 (0.47) | CES2MEN1THRBHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1304325-A1 | 5-(M-CYANOBENZYLAMINO)PYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-04-23 | — | — | EP | disclosed |
| CN-1030607-C | Tetracyclic compounds having anti-allergic and anti-asthmatic activities, their prepn. and use | SANKYO CO (JP) | 1996-01-03 | — | — | CN | disclosed |
| CN-1051360-A | Have agaist allergic symptoms and the active new tetracyclic compound of anti-asthma, its preparation and application | SANKYO CO (JP) | 1991-05-15 | — | — | CN | disclosed |