Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | GLS | O94925 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6928066 | 0.83 | ALDH1A1 (0.55) | TSHRALDH1A1GAAKDM4EMAPT | |
| SCHEMBL6928210 | 0.83 | ALDH1A1 (0.55) | TSHRALDH1A1GAAKDM4EMAPT | |
| SCHEMBL2754832 | 0.82 | TSHR (0.39) | TSHRGLSALDH1A1MGAMGAA | |
| SCHEMBL13289223 | 0.79 | ALDH1A1 (0.43) | TSHRALDH1A1CRBNGAAKDM4E | |
| SCHEMBL5489205 | 0.79 | TSHR (0.41) | TSHRGLSALDH1A1MGAMGAA | |
| SCHEMBL7917406 | 0.76 | NAMPT (0.38) | TSHRALDH1A1CRBNGAAKDM4E | |
| SCHEMBL364116 | 0.75 | — | — | |
| SCHEMBL13876758 | 0.75 | — | — | |
| SCHEMBL5168418 | 0.75 | — | — | |
| SCHEMBL29111068 | 0.74 | PSMB11 (0.37) | TSHRGLSALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0948587-B1 | FUEL COMPOSITIONS | INFINEUM HOLDINGS BV (NL) | 2003-05-07 | — | — | EP | disclosed |
| US-6312481-B1 | USE OF MONOAMIDE-CONTAINING POLYETHER ALCOHOL COMPOUNDS AS ADDITIVES TO DECREASE INTAKE VALVE DEPOSITS, CONTROL OCTANE REQUIREMENT INCREASE, AND REDUCE OCTANE REQUIREMENT. | SHELL OIL COMPANY | 2001-11-06 | — | — | US | disclosed |
| EP-0948587-A1 | FUEL COMPOSITIONS | Infineum Holdings BV (NL) | 1999-10-13 | — | — | EP | disclosed |
| WO-1998016599-A1 | FUEL COMPOSITIONS | INFINEUM HOLDINGS BV (NL) | 1998-04-23 | — | — | WO | disclosed |