Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | GLS | O94925 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | KDM5C | P41229 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.32 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7053704 | 0.79 | TSHR (0.42) | TSHRALDH1A1LMNAGLSKDM4E | |
| SCHEMBL13056340 | 0.79 | — | — | |
| SCHEMBL17080190 | 0.77 | CHRM2 (0.41) | TSHRLMNAKDM4EKMT2AMAPT | |
| SCHEMBL13542427 | 0.76 | TSHR (0.50) | TSHRALDH1A1LMNAKDM4EKMT2A | |
| SCHEMBL13056338 | 0.76 | TSHR (0.39) | TSHRALDH1A1LMNAGLSKDM4E | |
| SCHEMBL12155314 | 0.75 | KMT2A (0.53) | ALDH1A1LMNAKDM4EKMT2AMAPT | |
| SCHEMBL13876758 | 0.73 | — | — | |
| SCHEMBL364116 | 0.73 | — | — | |
| SCHEMBL8423451 | 0.73 | HDAC3 (0.52) | TSHRALDH1A1KDM4EKMT2AMAPT | |
| SCHEMBL12584010 | 0.73 | NAAA (0.39) | ALDH1A1LMNAKDM4EKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7186859-B2 | Uses for amino acid anticonvulsants | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 2007-03-06 | — | — | US | claimed |