Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 5/20 | 0.65 |
| ▸ | CDK8 | P49336 | 5/20 | 0.65 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | ICAM1 | P05362 | 13/20 | 0.53 |
| ▸ | SELE | P16581 | 12/20 | 0.53 |
| ▸ | VCAM1 | P19320 | 3/20 | 0.53 |
| ▸ | MAP3K8 | P41279 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7053724 | 1.00 | CCNC (0.65) | CCNCCDK8ESR1ICAM1SELE | |
| SCHEMBL7059457 | 0.81 | CCNC (0.69) | CCNCCDK8ICAM1SELEVCAM1 | |
| SCHEMBL7054426 | 0.80 | CCNC (0.80) | CCNCCDK8ICAM1SELEVCAM1 | |
| SCHEMBL7052854 | 0.80 | SELE (0.81) | CCNCCDK8ICAM1SELEMAP3K8 | |
| SCHEMBL7052862 | 0.80 | SELE (0.81) | CCNCCDK8ICAM1SELEMAP3K8 | |
| SCHEMBL7058294 | 0.79 | ICAM1 (0.78) | CCNCCDK8ICAM1SELEVCAM1 | |
| SCHEMBL7051837 | 0.79 | ICAM1 (0.83) | CCNCCDK8ICAM1SELEVCAM1 | |
| SCHEMBL7051830 | 0.79 | ICAM1 (0.83) | CCNCCDK8ICAM1SELEVCAM1 | |
| SCHEMBL7054707 | 0.79 | CCNC (0.79) | CCNCCDK8ICAM1SELEVCAM1 | |
| SCHEMBL5555774 | 0.79 | MAP3K8 (0.80) | CCNCCDK8ICAM1SELEVCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030220365-A1 | Cell adhesion-inhibiting antiinflammatory compounds | STEWART ANDREW O (US) | 2003-11-27 | — | — | US | disclosed |
| US-6232320-B1 | THIENO(2,3-C)PYRIDINE AND 5H-THIENO(2,3-C)PYRAN DERIATIVES | ABBOTT LABORATORIES | 2001-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220365-A1 | Cell adhesion-inhibiting antiinflammatory compounds | ICAM1, VCAM1, EPCAM | CCNC 1780/4885CDK8 2986/4885ESR1 2908/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.