SCHEMBL7053787

SCHEMBL7053787

CCCCCC(CCCCC)C(O)c1c(O)cccc1C(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
TSHR P16473 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
CA2 P00918 1/20 0.37
ATM Q13315 2/20 0.35
MAPT P10636 2/20 0.35
MEN1 O00255 1/20 0.35
HTT P42858 1/20 0.35
KMT2A Q03164 1/20 0.35
BID P55957 3/20 0.35
MCL1 Q07820 3/20 0.35
BCL2L1 Q07817 2/20 0.35
BAK1 Q16611 2/20 0.35
KAT8 Q9H7Z6 2/20 0.35
SAE1 Q9UBE0 2/20 0.35
PPARG P37231 1/20 0.35
PPARA Q07869 1/20 0.35
EP300 Q09472 1/20 0.35
KAT2A Q92830 1/20 0.35
KAT2B Q92831 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8761536 0.85 ALDH1A1 (0.44) ALDH1A1TSHRTDP1CA2ATM
SCHEMBL4596045 0.79 CYP2C9 (0.47) ALDH1A1TSHRTDP1CA2ATM
Hexane SCHEMBL27260332 0.72 ALDH1A1 (0.75) ALDH1A1TSHRTDP1CA2ATM
Heptane SCHEMBL27259929 0.71 ALDH1A1 (0.72) ALDH1A1TSHRTDP1CA2ATM
SCHEMBL21137911 0.71 MEN1 (0.44) ALDH1A1ATMMAPTMEN1HTT
SCHEMBL16054167 0.70 MEN1 (0.43) ALDH1A1ATMMAPTMEN1HTT
SCHEMBL7198536 0.70 ALDH1A1 (0.53) ALDH1A1TSHRTDP1CA2ATM
SCHEMBL28958219 0.69 ALDH1A1 (0.56) ALDH1A1TSHRTDP1CA2ATM
Pentane SCHEMBL27743488 0.69 ALDH1A1 (0.75) ALDH1A1TSHRTDP1CA2ATM
SCHEMBL4594554 0.69 ALDH1A1 (0.56) ALDH1A1TSHRTDP1CA2ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1304328-A1 PROCESS FOR THE PREPARATION OF A BENZOFURAN DERIVATIVE CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2003-04-23 EP disclosed