Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | P2RY12 | Q9H244 | 11/20 | 0.39 |
| ▸ | CNR2 | P34972 | 3/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7050548 | 0.92 | P2RY12 (0.39) | HTR6P2RY12MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7051550 | 0.92 | P2RY12 (0.39) | HTR6P2RY12MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7049255 | 0.91 | P2RY12 (0.39) | HTR6P2RY12MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7051730 | 0.90 | P2RY12 (0.38) | HTR6P2RY12MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7048587 | 0.90 | P2RY12 (0.40) | HTR6P2RY12MEN1KDM4EALDH1A1 | |
| SCHEMBL7052172 | 0.84 | HTR6 (0.31) | HTR6 | |
| SCHEMBL7054311 | 0.81 | HTT (0.41) | P2RY12MEN1KDM4EALDH1A1KMT2A | |
| SCHEMBL7051711 | 0.79 | HTT (0.39) | P2RY12MEN1KDM4EALDH1A1KMT2A | |
| SCHEMBL7047712 | 0.79 | HTT (0.39) | P2RY12MEN1KDM4EALDH1A1KMT2A | |
| SCHEMBL7049314 | 0.79 | HTT (0.39) | P2RY12MEN1KDM4EALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003022214-A2 | PIPERAZINE AND HOMOPIPERAZINE COMPOUNDS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2003-03-20 | — | — | WO | disclosed |