SCHEMBL705443

SCHEMBL705443

O=P(O)(O)OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O.[CaH2].[CaH2]

nearest known ligand 0.54

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 1/20 0.54
IGF2R P11717 7/20 0.53
AMDHD2 Q9Y303 1/20 0.47
LGALS8 O00214 1/20 0.46
LGALS3 P17931 1/20 0.46
LGALS4 P56470 1/20 0.46
AMY2A P04746 3/20 0.43
CA2 P00918 1/20 0.42
CD209 Q9NNX6 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL941549 0.99 FBP1 (0.55) FBP1IGF2RAMDHD2LGALS8LGALS3
SCHEMBL8883425 0.99 FBP1 (0.55) FBP1IGF2RAMDHD2LGALS8LGALS3
SCHEMBL7541942 0.99 FBP1 (0.55) FBP1IGF2RAMDHD2LGALS8LGALS3
SCHEMBL16701297 0.97 FBP1 (0.54) FBP1IGF2RAMDHD2LGALS8LGALS3
SCHEMBL29397911 0.95 IGF2R (0.50) FBP1IGF2RAMDHD2LGALS8LGALS3
SCHEMBL30017785 0.92 FBP1 (0.54) FBP1IGF2RAMDHD2LGALS8LGALS3
SCHEMBL29941534 0.88 FBP1 (0.53) FBP1IGF2RAMDHD2LGALS8LGALS3
Cellobiose SCHEMBL21777654 0.88 LGALS8 (0.52) IGF2RLGALS8LGALS3LGALS4AMY2A
Maltose SCHEMBL8343753 0.88 LGALS8 (0.54) IGF2RLGALS8LGALS3LGALS4AMY2A
Cellobiose SCHEMBL11512625 0.88 LGALS8 (0.54) IGF2RLGALS8LGALS3LGALS4AMY2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8124124-B2 Compressed tablet containing non-steroid antiinflammatory drug RECKITT BENCKISER HEALTHCARE (UK) LIMITED (GB) 2012-02-28 US disclosed
US-7771748-B2 Pharmaceutical compositions of 5,7,14-triazatetracyclo[10.3.1.02,11.04,9]-hexadeca-2(11),3,5,7,9-pentaene PFIZER INC (US) 2010-08-10 US disclosed
CN-100346774-C Treatment agent BOOTS CO PLC (GB) 2007-11-07 CN disclosed
EP-1448235-B1 ORAL CONTROLLED RELEASE PHARMACEUTICAL COMPOSITIONS OF 5,8,14-TRIAZATETRACYCLO 10.3.1.0(2,11).0(4,9)]-HEXADECA-2(11)3,5,7,9-PENTAENE PFIZER PROD INC (US) 2007-03-14 EP disclosed
EP-1235558-B1 COMPRESSED TABLET COMPOSITION COMPRISING A NSAID BOOTS CO PLC (GB) 2006-05-03 EP disclosed
EP-1448235-A1 PHARMACEUTICAL COMPOSITIONS OF 5,7,14-TRIAZATETRACYCLO 10.3.1.0(2,11).0(4,9)]-HEXADECA-2(11)3,5,7,9-PENTAENE Pfizer Products Inc. (US) 2004-08-25 EP disclosed
EP-1080081-B1 BENZOFUROXAN DERIVATIVES AND THEIR USE IN TREATING ANGINA PECTORIS TORRENT PHARMACEUTICALS LTD (IN) 2004-06-30 EP disclosed
US-20030203026-A1 Therapeutic agents RECKITT BENCKISER HEALTHCARE (UK) LIMITED (GB) 2003-10-30 US disclosed
US-20030180360-A1 Pharmaceutical compositions of 5,7,14-triazatetracyclo[10.3.1.02,11.04,9]-hexadeca-2 (11),3,5,7,9-pentaene PFIZER INC. 2003-09-25 US disclosed
CN-1433300-A Treatment agent BOOTS CO PLC (GB) 2003-07-30 CN disclosed
US-6232331-B1 TOLERANCE RESISTANT NITRIC OXIDE DONORS IN TREATMENT OF ANGINA PECTORIS TORRENT PHARMACEUTICAL LTD. (IN) 2001-05-15 US disclosed
EP-1080081-A1 BENZOFUROXAN DERIVATIVES AND THEIR USE IN TREATING ANGINA PECTORIS Torrent Pharmaceuticals Ltd (IN) 2001-03-07 EP disclosed
EP-1079829-A1 USE OF BENZOFUROXAN DERIVATIVES IN TREATING ANGINA PECTORIS Torrent Pharmaceuticals Ltd (IN) 2001-03-07 EP disclosed
WO-1999061018-A1 USE OF BENZOFUROXAN DERIVATIVES IN TREATING ANGINA PECTORIS SANKARANARAYANAN ALANGUDI (IN) 1999-12-02 WO disclosed
WO-1999061430-A1 BENZOFUROXAN DERIVATIVES AND THEIR USE IN TREATING ANGINA PECTORIS SANKARANARAYANAN ALANGUDI (IN) 1999-12-02 WO disclosed
US-5294644-A Nonionic surfactants for solubility ISP INVESTMENTS INC. (US) 1994-03-15 US disclosed
US-5093031-A Surface active lactams ISP INVESTMENTS INC. (US) 1992-03-03 US disclosed
EP-0311632-A4 SURFACE ACTIVE LACTAMS 1990-12-27 EP disclosed
EP-0311632-A1 SURFACE ACTIVE LACTAMS. GAF CORP (US) 1989-04-19 EP disclosed
WO-1988000184-A1 SURFACE ACTIVE LACTAMS GAF CORPORATION (US) 1988-01-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030180360-A1 Pharmaceutical compositions of 5,7,14-triazatetracyclo[10.3.1.02,11.04,9]-hexadeca-2 (11),3,5,7,9-pentaene CHRNA10, UGT1A10, CHRNA1 FBP1 1729/4885IGF2R 974/4885AMDHD2 2902/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.