Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | STS | P08842 | 1/20 | 0.44 |
| ▸ | RBP4 | P02753 | 1/20 | 0.44 |
| ▸ | IDE | P14735 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 3/20 | 0.43 |
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.43 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.43 |
| ▸ | LIPE | Q05469 | 1/20 | 0.43 |
| ▸ | TACR3 | P29371 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12632946 | 0.83 | CYP2C9 (0.58) | CYP2C9HDAC1HDAC6MEN1KMT2A | |
| SCHEMBL19385763 | 0.82 | MEN1 (0.52) | CYP2C9HDAC1HDAC6MEN1KMT2A | |
| SCHEMBL6772998 | 0.81 | LIPE (0.48) | CYP2C9HDAC1HDAC6SMN1; SMN2GPR119 | |
| SCHEMBL20657938 | 0.81 | MEN1 (0.55) | MEN1KMT2ASMN1; SMN2HTTNPSR1 | |
| SCHEMBL7049612 | 0.78 | MEN1 (0.55) | MEN1KMT2ASMN1; SMN2HTTNPSR1 | |
| SCHEMBL2365793 | 0.78 | MEN1 (0.58) | MEN1KMT2ASMN1; SMN2HTTNPSR1 | |
| SCHEMBL30208133 | 0.78 | MEN1 (0.58) | MEN1KMT2ASMN1; SMN2HTTNPSR1 | |
| SCHEMBL30591201 | 0.77 | CYP3A4 (0.56) | MEN1KMT2ASMN1; SMN2HTTNPSR1 | |
| SCHEMBL1907784 | 0.77 | CYP3A4 (0.56) | MEN1KMT2ASMN1; SMN2HTTNPSR1 | |
| SCHEMBL955402 | 0.77 | NR1H4 (0.55) | MEN1KMT2ASMN1; SMN2HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1222183-B1 | BENZOPYRAN DERIVATIVES | RECORDATI CHEM PHARM (IT) | 2003-04-23 | — | — | EP | disclosed |
| US-6403594-B1 | UROGENTIAL INFECTIONS, ETC | RECORDATI, S.A. CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 2002-06-11 | — | — | US | disclosed |