Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.69 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | PTPRC | P08575 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5336384 | 0.85 | TDP1 (0.65) | TDP1L3MBTL1MAOAMAOBPARP10 | |
| SCHEMBL5337623 | 0.85 | TDP1 (0.65) | TDP1L3MBTL1MAOAMAOBPARP10 | |
| SCHEMBL5334934 | 0.85 | TDP1 (0.65) | TDP1L3MBTL1MAOAMAOBPARP10 | |
| SCHEMBL16163453 | 0.84 | TDP1 (0.63) | TDP1L3MBTL1MAOAMAOBPARP10 | |
| SCHEMBL8076308 | 0.83 | CES1 (0.59) | TDP1L3MBTL1MAOAMAOBPARP10 | |
| SCHEMBL358939 | 0.83 | TDP1 (0.81) | TDP1L3MBTL1MAOAMAOBPARP10 | |
| SCHEMBL7052870 | 0.83 | PARP10 (0.58) | TDP1L3MBTL1MAOAMAOBPARP10 | |
| SCHEMBL7052871 | 0.82 | TDP1 (1.00) | TDP1L3MBTL1MAOAMAOBPARP10 | |
| SCHEMBL22797539 | 0.76 | TDP1 (0.77) | TDP1L3MBTL1MAOAMAOBPARP10 | |
| SCHEMBL16163913 | 0.76 | TDP1 (0.66) | TDP1L3MBTL1MAOAMAOBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042268-B1 | 1,7-DIBROMODIBENZOSUBERONE AND PROCEDURES FOR ITS PREPARATION | BELUPO LIJEKOVI I KOZMETIKA D (HR) | 2003-05-07 | — | — | EP | claimed |
| EP-1042268-B1 | 1,7-DIBROMODIBENZOSUBERONE AND PROCEDURES FOR ITS PREPARATION | BELUPO LIJEKOVI I KOZMETIKA D (HR) | 2003-05-07 | — | — | EP | disclosed |
| EP-1042268-A1 | DIBENZOSUBERONE DERIVATIVES AND PROCEDURES FOR THEIR PREPARATION | Belupo - Lijekovi I Kozmetika D.O.O. (HR) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999028284-A1 | DIBENZOSUBERONE DERIVATIVES AND PROCEDURES FOR THEIR PREPARATION | BELUPO - LIJEKOVI I KOZMETIKA D.O.O. (HR) | 1999-06-10 | — | — | WO | disclosed |