Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.49 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 3/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7052870 | 0.89 | PARP10 (0.58) | CES1TDP1L3MBTL1AKR1B1PARP10 | |
| SCHEMBL27537662 | 0.85 | PARP10 (0.46) | CES1TDP1L3MBTL1PARP10PARP11 | |
| SCHEMBL28322695 | 0.84 | MAOA (0.61) | CES1TDP1L3MBTL1AKR1B1PARP10 | |
| SCHEMBL7054532 | 0.83 | TDP1 (0.69) | CES1TDP1L3MBTL1AKR1B1PARP10 | |
| SCHEMBL7055100 | 0.83 | CES1 (0.60) | CES1TDP1L3MBTL1AKR1B1MAOA | |
| SCHEMBL16163913 | 0.81 | TDP1 (0.66) | CES1TDP1L3MBTL1AKR1B1MAOA | |
| SCHEMBL44496 | 0.80 | CES1 (0.90) | CES1TDP1L3MBTL1AKR1B1PARP10 | |
| SCHEMBL29408351 | 0.80 | CES1 (0.90) | CES1TDP1L3MBTL1AKR1B1PARP10 | |
| SCHEMBL29437756 | 0.80 | CES1 (0.90) | CES1TDP1L3MBTL1AKR1B1PARP10 | |
| SCHEMBL28158777 | 0.80 | PARP10 (0.42) | CES1TDP1L3MBTL1PARP10PARP11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042268-A1 | DIBENZOSUBERONE DERIVATIVES AND PROCEDURES FOR THEIR PREPARATION | Belupo - Lijekovi I Kozmetika D.O.O. (HR) | 2000-10-11 | — | — | EP | claimed |
| WO-1999028284-A1 | DIBENZOSUBERONE DERIVATIVES AND PROCEDURES FOR THEIR PREPARATION | BELUPO - LIJEKOVI I KOZMETIKA D.O.O. (HR) | 1999-06-10 | — | — | WO | claimed |
| EP-1042268-A1 | DIBENZOSUBERONE DERIVATIVES AND PROCEDURES FOR THEIR PREPARATION | Belupo - Lijekovi I Kozmetika D.O.O. (HR) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999028284-A1 | DIBENZOSUBERONE DERIVATIVES AND PROCEDURES FOR THEIR PREPARATION | BELUPO - LIJEKOVI I KOZMETIKA D.O.O. (HR) | 1999-06-10 | — | — | WO | disclosed |
| US-4003915-A | ANTICONVULSANTS, PARKINSON*S DISEASE | HOFFMANN-LA ROCHE INC. (US) | 1977-01-18 | — | — | US | disclosed |